Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.61 |
| ▸ | CTSS | P25774 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | PPARG | P37231 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KLK5 | Q9Y337 | 4/20 | 0.50 |
| ▸ | KLK7 | P49862 | 2/20 | 0.48 |
| ▸ | REN | P00797 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28594867 | 0.87 | PPARA (0.60) | PPARACTSSRAB9APPARGMEN1 | |
| SCHEMBL28594865 | 0.87 | PPARA (0.60) | PPARACTSSRAB9APPARGMEN1 | |
| SCHEMBL25467761 | 0.85 | PPARA (0.63) | PPARACTSSRAB9APPARGMEN1 | |
| SCHEMBL13537922 | 0.84 | PPARA (0.60) | PPARACTSSRAB9APPARGMEN1 | |
| SCHEMBL8430071 | 0.84 | PPARA (0.65) | PPARACTSSRAB9APPARGKLK5 | |
| SCHEMBL8428580 | 0.84 | PPARA (0.65) | PPARACTSSRAB9APPARGKLK5 | |
| SCHEMBL7338282 | 0.84 | PPARA (0.65) | PPARACTSSRAB9APPARGKLK5 | |
| SCHEMBL8734610 | 0.84 | PPARA (0.65) | PPARACTSSRAB9APPARGKLK5 | |
| SCHEMBL212796 | 0.84 | PPARA (0.65) | PPARACTSSRAB9APPARGMEN1 | |
| SCHEMBL212797 | 0.84 | PPARA (0.65) | PPARACTSSRAB9APPARGMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397370-B1 | BETA-BENZYLOXYASPARTATE DERIVATIVES WITH AMINO GROUP ON BENZENE RING | SUNTORY HOLDINGS LTD (JP) | 2014-07-23 | — | — | EP | disclosed |
| US-7666906-B2 | β-Benzyloxyaspartate derivatives with amino group on benzene ring | SUNTORY HOLDINGS LIMITED (JP) | 2010-02-23 | — | — | US | disclosed |
| US-7666906-B2 | β-Benzyloxyaspartate derivatives with amino group on benzene ring | SUNTORY HOLDINGS LIMITED (JP) | 2010-02-23 | — | — | US | disclosed |
| US-20070238783-A1 | Beta-benzyloxyaspartate derivatives with amino group on benzene ring | SUNTORY HOLDINGS LIMITED (JP) | 2007-10-11 | — | — | US | disclosed |
| US-20070238783-A1 | Beta-benzyloxyaspartate derivatives with amino group on benzene ring | SUNTORY HOLDINGS LIMITED (JP) | 2007-10-11 | — | — | US | disclosed |
| US-7247652-B2 | β-benzyloxyaspartate derivatives with amino group on benzene ring | SUNTORY LIMITED (JP) | 2007-07-24 | — | — | US | disclosed |
| US-7247652-B2 | β-benzyloxyaspartate derivatives with amino group on benzene ring | SUNTORY LIMITED (JP) | 2007-07-24 | — | — | US | disclosed |
| US-20040242652-A1 | Beta benzyloxyaspartate derivatives with amino group on benzene ring | SUNTORY HOLDINGS LTD. (JP) | 2004-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070238783-A1 | Beta-benzyloxyaspartate derivatives with amino group on benzene ring | SLC1A5, SLC7A1, SLC1A1 | PPARA 2091/4885CTSS 4242/4885RAB9A 2256/4885 |
| US-20040242652-A1 | Beta benzyloxyaspartate derivatives with amino group on benzene ring | SLC1A5, SLC1A1, SLC7A1 | PPARA 1847/4885CTSS 4493/4885RAB9A 2468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.