Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.65 |
| ▸ | PPARG | P37231 | 2/20 | 0.60 |
| ▸ | CTSS | P25774 | 3/20 | 0.58 |
| ▸ | KLK5 | Q9Y337 | 4/20 | 0.49 |
| ▸ | KLK7 | P49862 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 2/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8430071 | 1.00 | PPARA (0.65) | PPARAPPARGCTSSKLK5KLK7 | |
| SCHEMBL8426035 | 0.86 | PPARA (0.57) | PPARAPPARGCTSSKLK5SYK | |
| SCHEMBL6342945 | 0.84 | ATM (0.57) | PPARAPPARGCTSSKLK5ATM | |
| SCHEMBL11091464 | 0.84 | ATM (0.57) | PPARAPPARGCTSSKLK5ATM | |
| SCHEMBL29117201 | 0.84 | ATM (0.57) | PPARAPPARGCTSSKLK5ATM | |
| SCHEMBL3196374 | 0.84 | PPARA (0.61) | PPARAPPARGCTSSKLK5KLK7 | |
| SCHEMBL7450505 | 0.83 | PPARA (0.60) | PPARAPPARGCTSSKLK5KLK7 | |
| SCHEMBL828674 | 0.83 | PPARA (0.90) | PPARAPPARGCTSSKLK5KLK7 | |
| SCHEMBL1132901 | 0.83 | PPARA (0.90) | PPARAPPARGCTSSKLK5KLK7 | |
| SCHEMBL17051 | 0.83 | PPARA (0.90) | PPARAPPARGCTSSKLK5KLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962660-A | COMPOUND WHICH SUPPRESSES SELECTIN-MEDIATED CELLULAR ADHESION; FOR STABLE ANTIINFLAMMATORY AGENTS WITH BETTER BIOAVAILABILITY AND GREATER ACTIVITY WHICH ARE EASIER TO SYNTHESIZE | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-10-05 | — | — | US | disclosed |