Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.63 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.56 |
| ▸ | DUT | P33316 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12264131 | 0.85 | KIF11 (0.74) | KIF11KCNN4DUTTSHRALDH1A1 | |
| SCHEMBL574703 | 0.84 | KIF11 (0.47) | KIF11KCNN4IDO1 | |
| SCHEMBL4254994 | 0.82 | KCNN4 (0.44) | KIF11KCNN4DUTTSHRIDO1 | |
| SCHEMBL12264133 | 0.81 | KIF11 (0.68) | KIF11KCNN4DUTTSHRALDH1A1 | |
| SCHEMBL29679194 | 0.79 | KIF11 (0.65) | KIF11KCNN4DUTTSHRALDH1A1 | |
| SCHEMBL147990 | 0.79 | KIF11 (0.65) | KIF11KCNN4DUTALDH1A1 | |
| SCHEMBL9781955 | 0.77 | KIF11 (0.63) | KIF11KCNN4DUTTSHRALDH1A1 | |
| SCHEMBL1809571 | 0.77 | KIF11 (0.63) | KIF11KCNN4DUTTSHRALDH1A1 | |
| SCHEMBL8961063 | 0.77 | KCNN4 (0.68) | KIF11KCNN4DUTTAAR1 | |
| SCHEMBL1105545 | 0.77 | KIF11 (1.00) | KIF11KCNN4DUTTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3066106-A1 | STABLE PANTETHEINE DERIVATIVES FOR THE TREATMENT OF PANTOTHENATE KINASE ASSOCIATED NEURODEGENERATION (PKAN) AND METHODS FOR THE SYNTHESIS OF SUCH COMPOUNDS | Acies Bio d.o.o. (SI) | 2016-09-14 | — | — | EP | claimed |
| WO-2015063177-A1 | STABLE PANTETHEINE DERIVATIVES FOR THE TREATMENT OF PANTOTHENATE KINASE ASSOCIATED NEURODEGENERATION (PKAN) AND METHODS FOR THE SYNTHESIS OF SUCH COMPOUNDS | ACIES BIO D.O.O. (SI) | 2015-05-07 | — | — | WO | claimed |
| CN-120059164-A | PH responsive polypeptide mimic and preparation method and application thereof | 华东理工大学 | 2025-05-30 | — | — | CN | disclosed |
| CN-113185740-B | Method for improving antibacterial activity and biocompatibility of substrate surface | 华东理工大学 | 2023-09-22 | — | — | CN | disclosed |
| CN-116554461-A | Use of polymers to promote endothelialization of interventional/implant materials | 华东理工大学 | 2023-08-08 | — | — | CN | disclosed |
| US-20220133753-A1 | COMPOSITIONS AND METHODS USEFUL FOR TREATING DISEASES CHARACTERIZED BY INSUFFICIENT PANTOTHENATE KINASE ACTIVITY | VECTIVBIO COMET AG, F/K/A COMET THERAPEUTICS, INC. (CH) | 2022-05-05 | — | — | US | disclosed |
| EP-2459227-B1 | Prodrugs containing an aromatic amine connected by an amide bond to a carrier | ASCENDIS PHARMA AS (DK) | 2021-03-17 | — | — | EP | disclosed |
| EP-2741782-B1 | PROTEIN CARRIER-LINKED PRODRUGS | ASCENDIS PHARMA AS (DK) | 2020-05-06 | — | — | EP | disclosed |
| CN-110478495-A | Target conjugate and its particle and preparation | TARVEDA THERAPEUTICS INC | 2019-11-22 | — | — | CN | disclosed |
| CN-106573077-B | Targeted conjugates and particles and formulations thereof | 塔弗达治疗有限公司 | 2019-07-30 | — | — | CN | disclosed |
| US-20170227545-A1 | REACTIVITY-BASED SCREENING FOR NATURAL PRODUCT DISCOVERY | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS | 2017-08-10 | — | — | US | disclosed |
| US-5079358-A | Humans; leukemia | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-01-07 | — | — | US | disclosed |
| EP-0347749-A2 | Pyrazoloacridone derivatives with anti-tumoral activity | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1989-12-27 | — | — | EP | disclosed |
| US-4863935-A | Mitomycin compounds having useful anti-tumor activity | KYOWA HAKKO KOGYO K.K. (JP) | 1989-09-05 | — | — | US | disclosed |
| EP-0272063-A1 | Mitomycin derivatives | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JP) | 1988-06-22 | — | — | EP | disclosed |
| EP-0002564-B1 | DERIVATIVES OF 7-OXO-1-AZABICYCLO(3.2.0)-HEPT-2-ENE-2-CARBOXYLIC ACID, THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND INTERMEDIATES | BEECHAM GROUP PLC (GB) | 1984-06-20 | — | — | EP | disclosed |
| US-4347181-A | Intermediates for producing bicyclic β-lactam-antibiotics | BEECHAM GROUP LIMITED (GB) | 1982-08-31 | — | — | US | disclosed |
| US-4289696-A | BETA-LACTAMASE INHIBITORY AGENTS WHICH ENHANCE ACTIVITY OF A PENICICILLIN OR CEPHALOSPORIN | BEECHAM GROUP LIMITED (GB) | 1981-09-15 | — | — | US | disclosed |
| US-4223038-A | THIENAMYCINS | BEECHAM GROUP LIMITED (GB) | 1980-09-16 | — | — | US | disclosed |
| EP-0002564-A1 | Derivatives of 7-oxo-1-azabicyclo(3.2.0)-hept-2-ene-2-carboxylic acid, their preparation, pharmaceutical compositions containing them and intermediates | BEECHAM GROUP PLC (GB) | 1979-06-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220133753-A1 | COMPOSITIONS AND METHODS USEFUL FOR TREATING DISEASES CHARACTERIZED BY INSUFFICIENT PANTOTHENATE KINASE ACTIVITY | PANK1, PANK3, PHKG1 | KIF11 4141/4885KCNN4 3189/4885DUT 602/4885 |
| US-20170227545-A1 | REACTIVITY-BASED SCREENING FOR NATURAL PRODUCT DISCOVERY | NQO1, NCL, NANS | KIF11 3852/4885KCNN4 3864/4885DUT 441/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.