Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3201661 | 0.84 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1HTTTP53 | |
| SCHEMBL21242971 | 0.83 | ALDH1A1 (0.41) | ALDH1A1KMT2AMEN1HTTTP53 | |
| SCHEMBL20707153 | 0.82 | ALDH1A1 (0.48) | ALDH1A1KMT2AMEN1HTTTP53 | |
| SCHEMBL15881333 | 0.79 | ALDH1A1 (0.40) | ALDH1A1KMT2AMEN1HTTTP53 | |
| SCHEMBL15882546 | 0.79 | ALDH1A1 (0.40) | ALDH1A1KMT2AMEN1HTTTP53 | |
| SCHEMBL9345103 | 0.79 | ALDH1A1 (0.40) | ALDH1A1KMT2AMEN1HTTTP53 | |
| SCHEMBL12310446 | 0.79 | ALDH1A1 (0.40) | ALDH1A1KMT2AMEN1HTTTP53 | |
| SCHEMBL9345095 | 0.79 | ALDH1A1 (0.40) | ALDH1A1KMT2AMEN1HTTTP53 | |
| SCHEMBL28899825 | 0.78 | LMNA (0.40) | ALDH1A1KMT2AMEN1HTTTP53 | |
| SCHEMBL21119144 | 0.76 | ALDH1A1 (0.44) | ALDH1A1KMT2AMEN1HTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7683185-B2 | Histone deacetylase inhibitors | QUEEN MARY & WESTFIELD COLLEGE (GB) | 2010-03-23 | — | — | US | claimed |
| US-20060235231-A1 | 6-(4-Dimethylamino-phenylsulfanyl)-hexa-2,4-dienoic acid methyl ester; stimulating hematopoietic cells ex vivo | UCL BIOMEDICA PLC (GB) | 2006-10-19 | — | — | US | claimed |
| EP-1565432-A1 | HISTONE DEACETYLASE INHIBITORS | QUEEN MARY & WESTFIELD COLLEGE (GB) | 2005-08-24 | — | — | EP | claimed |
| WO-2004046094-A9 | HISTONE DEACETYLASE INHIBITORS | QUEEN MARY & WESTFIELD COLLEGE (GB) | 2005-06-23 | — | — | WO | claimed |
| WO-2004046094-A1 | HISTONE DEACETYLASE INHIBITORS | QUEEN MARY & WESTFIELD COLLEGE (GB) | 2004-06-03 | — | — | WO | claimed |
| US-7683185-B2 | Histone deacetylase inhibitors | QUEEN MARY & WESTFIELD COLLEGE (GB) | 2010-03-23 | — | — | US | disclosed |
| US-20060235231-A1 | 6-(4-Dimethylamino-phenylsulfanyl)-hexa-2,4-dienoic acid methyl ester; stimulating hematopoietic cells ex vivo | UCL BIOMEDICA PLC (GB) | 2006-10-19 | — | — | US | disclosed |
| EP-1565432-A1 | HISTONE DEACETYLASE INHIBITORS | QUEEN MARY & WESTFIELD COLLEGE (GB) | 2005-08-24 | — | — | EP | disclosed |
| WO-2004046094-A9 | HISTONE DEACETYLASE INHIBITORS | QUEEN MARY & WESTFIELD COLLEGE (GB) | 2005-06-23 | — | — | WO | disclosed |
| WO-2004046094-A1 | HISTONE DEACETYLASE INHIBITORS | QUEEN MARY & WESTFIELD COLLEGE (GB) | 2004-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060235231-A1 | 6-(4-Dimethylamino-phenylsulfanyl)-hexa-2,4-dienoic acid methyl ester; stimulating hematopoietic cells ex vivo | HDAC1, HDAC7, HDAC5 | ALDH1A1 1199/4885KMT2A 38/4885MEN1 1781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.