SCHEMBL3198125

SCHEMBL3198125

Cc1cc(C)c(NN=C(CC2=C(N(C)C)C=CC2)c2ccccc2)c(C)c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.34
ALDH1A1 P00352 7/20 0.34
SMN1; SMN2 Q16637 5/20 0.34
KMT2A Q03164 5/20 0.34
LMNA P02545 4/20 0.34
MEN1 O00255 4/20 0.34
RAB9A P51151 3/20 0.34
TDP1 Q9NUW8 4/20 0.34
GAA P10253 3/20 0.34
HTT P42858 3/20 0.34
KDM4E B2RXH2 2/20 0.34
THRB P10828 1/20 0.34
HPGD P15428 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
NPC1 O15118 1/20 0.32
FFAR4 Q5NUL3 1/20 0.32
NPSR1 Q6W5P4 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3215047 0.86 MAPT (0.37) MAPTALDH1A1SMN1; SMN2KMT2ALMNA
SCHEMBL3198512 0.86 ALDH1A1 (0.43) MAPTALDH1A1SMN1; SMN2KMT2ALMNA
SCHEMBL3215674 0.85 MAPT (0.36) MAPTALDH1A1SMN1; SMN2KMT2ALMNA
SCHEMBL3211382 0.83 KMT2A (0.38) MAPTALDH1A1SMN1; SMN2KMT2ALMNA
SCHEMBL3199281 0.82 KMT2A (0.34) MAPTALDH1A1SMN1; SMN2KMT2ALMNA
SCHEMBL3210932 0.81 ALDH1A1 (0.38) MAPTALDH1A1SMN1; SMN2KMT2ALMNA
SCHEMBL3203610 0.80 ALDH1A1 (0.36) MAPTALDH1A1SMN1; SMN2KMT2ALMNA
SCHEMBL3212363 0.76 SMN1; SMN2 (0.36) MAPTALDH1A1SMN1; SMN2KMT2ALMNA
SCHEMBL3213519 0.76 KMT2A (0.36) MAPTALDH1A1SMN1; SMN2KMT2ALMNA
SCHEMBL3200005 0.76 KMT2A (0.38) MAPTALDH1A1SMN1; SMN2KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7732643-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-08 US disclosed
US-7671226-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-02 US disclosed
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME HANAOKA HIDENORI 2010-02-25 US disclosed
EP-1426379-B1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME SUMITOMO CHEMICAL CO (JP) 2009-11-11 EP disclosed
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same HANAOKA HIDENORI 2009-02-26 US disclosed
US-7439379-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL CO., LTD. (JP) 2008-10-21 US disclosed
US-20040242410-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-02 US disclosed
EP-1426379-A1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME Sumitomo Chemical Company, Limited (JP) 2004-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same C1R, C1S, AP1M1 MAPT 2641/4885ALDH1A1 1229/4885SMN1; SMN2 3599/4885
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME C1R, C1S, AP1M1 MAPT 2641/4885ALDH1A1 1229/4885SMN1; SMN2 3599/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.