SCHEMBL3200005

SCHEMBL3200005

CC1=C(C)C(C)=C(CC(=NNc2c(C)cc(C)cc2C)c2ccccc2)C1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.38
MEN1 O00255 5/20 0.38
RAB9A P51151 2/20 0.38
MAPT P10636 10/20 0.37
ALDH1A1 P00352 7/20 0.37
SMN1; SMN2 Q16637 7/20 0.37
GAA P10253 5/20 0.37
KDM4E B2RXH2 4/20 0.37
TDP1 Q9NUW8 4/20 0.37
LMNA P02545 3/20 0.37
HTT P42858 2/20 0.37
HPGD P15428 2/20 0.37
THRB P10828 1/20 0.37
NPC1 O15118 2/20 0.36
NPSR1 Q6W5P4 2/20 0.35
CRHBP P24387 1/20 0.35
CRHR2 Q13324 1/20 0.35
TAAR1 Q96RJ0 1/20 0.34
CTSL P07711 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3213326 0.85 ALDH1A1 (0.48) KMT2AMEN1RAB9AMAPTALDH1A1
SCHEMBL3214936 0.83 MAPT (0.38) KMT2AMEN1RAB9AMAPTALDH1A1
SCHEMBL3202326 0.82 MAPT (0.37) KMT2AMEN1RAB9AMAPTALDH1A1
SCHEMBL3213519 0.82 KMT2A (0.36) KMT2AMEN1RAB9AMAPTALDH1A1
SCHEMBL3685517 0.81 KMT2A (0.41) KMT2AMEN1MAPTALDH1A1SMN1; SMN2
SCHEMBL3199470 0.80 ALDH1A1 (0.42) KMT2AMEN1RAB9AMAPTALDH1A1
SCHEMBL3212263 0.80 MAPT (0.37) KMT2AMEN1RAB9AMAPTALDH1A1
SCHEMBL3215047 0.80 MAPT (0.37) KMT2AMEN1RAB9AMAPTALDH1A1
SCHEMBL3191554 0.78 CTSL (0.35) KMT2AMEN1MAPTALDH1A1SMN1; SMN2
SCHEMBL3198125 0.76 MAPT (0.34) KMT2AMEN1RAB9AMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7732643-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-08 US disclosed
US-7671226-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-02 US disclosed
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME HANAOKA HIDENORI 2010-02-25 US disclosed
EP-1426379-B1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME SUMITOMO CHEMICAL CO (JP) 2009-11-11 EP disclosed
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same HANAOKA HIDENORI 2009-02-26 US disclosed
US-7439379-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL CO., LTD. (JP) 2008-10-21 US disclosed
US-20040242410-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-02 US disclosed
EP-1426379-A1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME Sumitomo Chemical Company, Limited (JP) 2004-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same C1R, C1S, AP1M1 KMT2A 2101/4885MEN1 1101/4885RAB9A 1759/4885
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME C1R, C1S, AP1M1 KMT2A 2101/4885MEN1 1101/4885RAB9A 1759/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.