SCHEMBL3198147

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3183847	0.83	HDAC6 (0.59)	HSD17B2HSD17B1KDM4ENPC1ALDH1A1
	SCHEMBL3195203	0.79	SMN1; SMN2 (0.48)	SMN1; SMN2TP53KDM4ENPC1ALDH1A1
	SCHEMBL6477476	0.79	KDM4E (0.58)	HSD17B2HSD17B1SMN1; SMN2TP53KDM4E
	SCHEMBL5420514	0.79	RAB9A (0.58)	HSD17B2HSD17B1KDM4ENPC1ALDH1A1
	SCHEMBL23091231	0.78	SMN1; SMN2 (0.53)	SMN1; SMN2TP53KDM4ENPC1ALDH1A1
	SCHEMBL3098145	0.78	HDAC6 (0.72)	SMN1; SMN2TP53KDM4ENPC1ALDH1A1
	SCHEMBL1587411	0.77	NPSR1 (0.53)	SMN1; SMN2KDM4ENPC1ALDH1A1GLA
	SCHEMBL5937292	0.77	ALDH1A1 (0.55)	SMN1; SMN2KDM4EALDH1A1MAPTHPGD
	SCHEMBL29906326	0.76	CA1 (0.50)	SMN1; SMN2TP53KDM4EALDH1A1GAA
	SCHEMBL27108460	0.76	ALDH1A1 (0.55)	SMN1; SMN2TP53KDM4ENPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.