Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.54 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2434774 | 0.83 | PTPN22 (0.58) | PTPN22LDHAPOLBHSD17B10ALDH1A1 | |
| SCHEMBL29466047 | 0.83 | PTPN22 (0.58) | PTPN22LDHAPOLBHSD17B10ALDH1A1 | |
| SCHEMBL30187599 | 0.83 | PTPN22 (0.58) | PTPN22LDHAPOLBHSD17B10ALDH1A1 | |
| SCHEMBL2233625 | 0.83 | PTPN22 (0.58) | PTPN22LDHAPOLBHSD17B10ALDH1A1 | |
| SCHEMBL6754155 | 0.81 | PTPN22 (0.56) | PTPN22LDHAPOLBHSD17B10ALDH1A1 | |
| SCHEMBL6035055 | 0.79 | PTPN22 (0.54) | PTPN22LDHAHSD17B10ALDH1A1CYP2A6 | |
| SCHEMBL11467447 | 0.79 | PTPN22 (0.54) | PTPN22LDHAHSD17B10ALDH1A1CYP2A6 | |
| SCHEMBL28572809 | 0.76 | PTPN22 (0.50) | PTPN22LDHAHSD17B10ALDH1A1CYP2A6 | |
| SCHEMBL4969506 | 0.76 | PTPN22 (0.50) | PTPN22LDHAHSD17B10ALDH1A1CYP2A6 | |
| SCHEMBL28567124 | 0.76 | PTPN22 (0.46) | PTPN22LDHAPOLBUSP2PAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7666953-B2 | Phosphine-protonated haloaromatic compound accelerator with curing resin and curing agent | HITACHI CHEMICAL CO, LTD. (JP) | 2010-02-23 | — | — | US | disclosed |
| US-20090005480-A1 | REACTION PRODUCT OF PHOSPHINE AND PROTONATED HALOARYL COMPOUND AND USE AS EPOXY CURING ACCELERATOR | NAKAMURA SHINYA | 2009-01-01 | — | — | US | disclosed |
| US-20050267286-A1 | Curing accelerator for curing resin, curing resin composition, electronic component device and method for producing phosphine derivative | HITACHI CHEMICAL CO., LTD. (JP) | 2005-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090005480-A1 | REACTION PRODUCT OF PHOSPHINE AND PROTONATED HALOARYL COMPOUND AND USE AS EPOXY CURING ACCELERATOR | HDHD5, EHMT2, HRH2 | PTPN22 4240/4885LDHA 2160/4885POLB 369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.