Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.60 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.60 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.45 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TOP1 | P11387 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3198715 | 1.00 | ALDH1A1 (0.60) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| Sitafloxacin Anhydrous SCHEMBL8509346 | 0.90 | ALDH1A1 (0.59) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| Sitafloxacin Anhydrous SCHEMBL29821427 | 0.90 | ALDH1A1 (0.59) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| Sitafloxacin Anhydrous SCHEMBL2784482 | 0.90 | ALDH1A1 (0.59) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| Sitafloxacin Anhydrous SCHEMBL29368438 | 0.90 | ALDH1A1 (0.59) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| Sitafloxacin Anhydrous SCHEMBL74553 | 0.90 | ALDH1A1 (0.59) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| Sitafloxacin Anhydrous SCHEMBL13483604 | 0.90 | ALDH1A1 (0.59) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| Sitafloxacin Anhydrous SCHEMBL1652843 | 0.90 | ALDH1A1 (0.59) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| Sitafloxacin Anhydrous SCHEMBL21416358 | 0.90 | ALDH1A1 (0.59) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| Sitafloxacin Anhydrous SCHEMBL3198924 | 0.90 | ALDH1A1 (0.59) | ALDH1A1POLBOPRM1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE41149-E1 | Stereoisomerically pure 7-[(7S)-7-amino-5-azaspiro[2.4]heptan-5-yl]-6-fluoro-1-[(1R,2S)-2-fluoro-1-cyclopropyl]-8-methoxy-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid or a pharmaceutically acceptable salt thereof; antibacterial agents | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2010-02-23 | — | — | US | disclosed |
| US-6031102-A | Optically active pyridonecarboxylic acid derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2000-02-29 | — | — | US | disclosed |
| US-5587386-A | BACTERICIDES, MICROBIOCIDES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |