Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.64 |
| ▸ | LCK | P06239 | 1/20 | 0.64 |
| ▸ | FYN | P06241 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | LDHB | P07195 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL1150955 | 1.00 | FFAR3 (0.64) | FFAR3LCKFYNLMNAALOX15 | |
| Acetic Acid SCHEMBL159615 | 1.00 | FFAR3 (0.64) | FFAR3LCKFYNLMNAALOX15 | |
| Acetic Acid SCHEMBL16269468 | 1.00 | FFAR3 (0.64) | FFAR3LCKFYNLMNAALOX15 | |
| Acetic Acid SCHEMBL1715034 | 0.86 | — | — | |
| Acetic Acid SCHEMBL27827411 | 0.86 | LMNA (0.80) | FFAR3LCKFYNLMNAALOX15 | |
| Acetic Acid SCHEMBL27616022 | 0.86 | FFAR3 (0.70) | FFAR3LCKFYNLMNAALOX15 | |
| Acetic Acid SCHEMBL875913 | 0.86 | — | — | |
| Acetic Acid SCHEMBL2776984 | 0.86 | — | — | |
| Acetic Acid SCHEMBL30298819 | 0.86 | FFAR3 (0.70) | FFAR3LCKFYNLMNAALOX15 | |
| Acetic Acid SCHEMBL28385300 | 0.86 | LMNA (0.80) | FFAR3LCKFYNLMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590977-B1 | FLUORESCENT CARBAPENEMS | PFAENDLER HANS RUDOLF (DE) | 2022-06-29 | — | — | EP | disclosed |
| US-9969737-B2 | Fluorescent carbapenems | HANS RUDOLF PFAENDLER (DE) | 2018-05-15 | — | — | US | disclosed |
| US-20160251356-A1 | FLUORESCENT CARBAPENEMS | PFAENDLER HANS RUDOLF | 2016-09-01 | — | — | US | disclosed |
| US-9296752-B2 | Fluorescent carbapenems | Pfaendler, Hans R. (DE) | 2016-03-29 | — | — | US | disclosed |
| EP-2590977-A1 | FLUORESCENT CARBAPENEMS | Pfaendler, Hans Rudolf (DE) | 2013-05-15 | — | — | EP | disclosed |
| US-20130102017-A1 | FLUORESCENT CARBAPENEMS | Pfaendler, Hans Rudolf (DE) | 2013-04-25 | — | — | US | disclosed |
| WO-2012003955-A1 | FLUORESCENT CARBAPENEMS | PFAENDLER HANS RUDOLF (DE) | 2012-01-12 | — | — | WO | disclosed |
| EP-1732990-B1 | CATIONIC IMIDAZOLAZO DYES CONTAINING A 2,5-DIAMINOPHENYL MOIETY | BASF SE (DE) | 2011-09-07 | — | — | EP | disclosed |
| US-7482438-B2 | Cationic imidazolazo dyes containing a 2,5-diaminophenyl moiety | CIBA SPECIALTY CHEMICALS CORP. (US) | 2009-01-27 | — | — | US | disclosed |
| US-20070214580-A1 | Cationic Imidazolazo Dyes Containing A 2,5-Diaminophenyl | CIBA SPECIALTY CHEMICALS CORP. | 2007-09-20 | — | — | US | disclosed |
| CN-1965033-A | Cationic imidazolazo dyes containing a 2,5-diaminophenyl moiety | CIBA SC HOLDING AG (CH) | 2007-05-16 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130102017-A1 | FLUORESCENT CARBAPENEMS | MGAM, MCRS1, ADSL | FFAR3 2162/4885LCK 4823/4885FYN 4811/4885 |
| US-20160251356-A1 | FLUORESCENT CARBAPENEMS | MGAM, MCRS1, ADSL | FFAR3 2162/4885LCK 4823/4885FYN 4811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.