Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 1/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.54 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 8/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28022689 | 0.93 | ALOX5 (0.56) | CLK1DYRK1ADYRK1BESR1KMT2A | |
| SCHEMBL767398 | 0.91 | ESR1 (0.49) | CLK1DYRK1ADYRK1BESR1KMT2A | |
| SCHEMBL10630235 | 0.84 | ESR1 (0.53) | ESR1KMT2AMEN1ALOX5NPC1 | |
| SCHEMBL4596186 | 0.83 | ALOX5 (0.62) | ESR1KMT2AMEN1ALOX5RAB9A | |
| SCHEMBL28886219 | 0.82 | ALOX5 (0.50) | ESR1KMT2AMEN1ALOX5NPC1 | |
| SCHEMBL8756192 | 0.81 | SLC2A1 (0.61) | CLK1DYRK1ADYRK1BESR1KMT2A | |
| SCHEMBL8756174 | 0.81 | ESR1 (0.51) | ESR1KMT2ASLC2A1SLC2A4MEN1 | |
| SCHEMBL16660338 | 0.81 | KMT2A (0.49) | CLK1DYRK1ADYRK1BESR1KMT2A | |
| SCHEMBL28373149 | 0.81 | ALOX5 (0.49) | ESR1KMT2AMEN1ALOX5NPC1 | |
| SCHEMBL10921870 | 0.80 | ALOX5 (0.66) | ESR1KMT2ASLC2A1SLC2A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101175836-B | Compounds comprising 2, 6-naphthyl groups | BASF SE (DE) | 2013-04-03 | — | — | CN | disclosed |
| US-7670505-B2 | Compounds comprising 2,6-naphthyl groups | BASF AKTIENGESELLSCHAFT (DE) | 2010-03-02 | — | — | US | disclosed |
| US-20080221289-A1 | Compounds Comprising 2,6-Naphthyl Groups | BASF AKTIENGESELLSCHAFT (DE) | 2008-09-11 | — | — | US | disclosed |
| CN-101175836-A | Compounds comprising 2, 6-naphthyl groups | BASF AG (DE) | 2008-05-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221289-A1 | Compounds Comprising 2,6-Naphthyl Groups | SCO2, MT-CO1, CBR1 | CLK1 3956/4885DYRK1A 4034/4885DYRK1B 4276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.