Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 8/20 | 0.52 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.52 |
| ▸ | HTR3B | O95264 | 1/20 | 0.52 |
| ▸ | HTR3A | P46098 | 1/20 | 0.52 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.52 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | BPTF | Q12830 | 1/20 | 0.43 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4246315 | 0.79 | KHK (0.57) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL15378488 | 0.79 | KHK (0.57) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL4246310 | 0.79 | KHK (0.57) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL2291787 | 0.78 | ADRB1 (0.58) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL30889351 | 0.78 | ADRB1 (0.52) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL28026638 | 0.78 | ADRB1 (0.52) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL236047 | 0.78 | ADRB1 (0.52) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL4423739 | 0.78 | ADRB1 (0.52) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| Hydrochloric Acid SCHEMBL15819287 | 0.78 | KHK (0.56) | ADRB1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL6907013 | 0.77 | ADRB1 (0.60) | ADRB1HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118834189-A | Light-induced fluorescence excitation probe, indazolone compound, and preparation methods and applications thereof | 国科大杭州高等研究院 | 2024-10-25 | — | — | CN | claimed |
| CN-118126053-A | Synthesis and application of difunctional fluorescent probe for simultaneously distinguishing mercury ions and amyloid proteins | 湖南师范大学 | 2024-06-04 | — | — | CN | claimed |
| CN-115477657-B | Coumarin prodrug and preparation method and application thereof | 中国药科大学 | 2023-10-31 | — | — | CN | claimed |
| CN-112940709-B | Self-flashing rhodamine spirothioester fluorescent dye, synthetic method thereof and application thereof in super-resolution imaging field | 中国科学院大连化学物理研究所 | 2023-02-21 | — | — | CN | claimed |
| CN-115477657-A | Coumarin prodrug and preparation method and application thereof | 中国药科大学 | 2022-12-16 | — | — | CN | claimed |
| CN-109516969-B | Carboxyl-containing coumarin derivative and synthesis method and application thereof | 山西大学 | 2022-03-18 | — | — | CN | claimed |
| CN-110117295-B | Fluorescent probe for detecting mercury ions and preparation method and application thereof | 江汉大学 | 2021-11-30 | — | — | CN | claimed |
| CN-112940709-A | Self-flashing rhodamine spirothioester fluorescent dye, synthetic method thereof and application thereof in super-resolution imaging field | 中国科学院大连化学物理研究所 | 2021-06-11 | — | — | CN | claimed |
| CN-109370573-B | Fluorescent probe for detecting bivalent mercury ions and temperature, preparation method and application thereof | 江汉大学 | 2021-05-18 | — | — | CN | claimed |
| CN-110964022-A | Fluorescent probe for detecting peroxynitrite ions and preparation method and application thereof | 济南大学 | 2020-04-07 | — | — | CN | claimed |
| CN-106699690-B | A kind of pleuromutilin derivative and its preparation method and application with acyl piperazine base side chain | 华南农业大学 | 2019-09-10 | — | — | CN | claimed |
| CN-106699690-A | Pleuromulin derivative with acyl piperazine side chain and preparing method and application of pleuromulin derivative | 华南农业大学 | 2017-05-24 | — | — | CN | claimed |
| CN-120157666-A | Dihydropyrimidine compound, preparation method and application thereof, dihydropyrimidine derivative and application thereof, pharmaceutical composition and application thereof | 中国医学科学院医药生物技术研究所 | 2025-06-17 | — | — | CN | disclosed |
| CN-119859122-B | Tyrosinase inhibitor and preparation method and application thereof | 杭州师范大学 | 2025-06-13 | — | — | CN | disclosed |
| CN-119859122-A | Tyrosinase inhibitor and preparation method and application thereof | 杭州师范大学 | 2025-04-22 | — | — | CN | disclosed |
| CN-118834189-A | Light-induced fluorescence excitation probe, indazolone compound, and preparation methods and applications thereof | 国科大杭州高等研究院 | 2024-10-25 | — | — | CN | disclosed |
| US-20100029682-A1 | NOVEL CHROMENE AND THIOCHROMENE CARBOXAMIDE DERIVATIVES, METHODS FOR PREPARING SAME AND THERAPEUTIC APPLICATIONS OF SAME | PIERRE FABRE MEDICAMENT (FR) | 2010-02-04 | — | — | US | disclosed |
| CN-101490030-A | Novel benzopyran and 1, 2-benzothiopyranamide derivatives, preparation thereof and therapeutic use thereof | PF MEDICAMENT (FR) | 2009-07-22 | — | — | CN | disclosed |
| EP-2057138-A1 | NOVEL CHROMENE AND THIOCHROMENE CARBOXAMIDE DERIVATIVES, METHODS FOR PREPARING SAME AND THERAPEUTIC APPLICATIONS OF SAME | Pierre Fabre Medicament (FR) | 2009-05-13 | — | — | EP | disclosed |
| WO-2008009741-A1 | NOVEL CHROMENE AND THIOCHROMENE CARBOXAMIDE DERIVATIVES, METHODS FOR PREPARING SAME AND THERAPEUTIC APPLICATIONS OF SAME | PIERRE FABRE MEDICAMENT (FR) | 2008-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029682-A1 | NOVEL CHROMENE AND THIOCHROMENE CARBOXAMIDE DERIVATIVES, METHODS FOR PREPARING SAME AND THERAPEUTIC APPLICATIONS OF SAME | DRD3, CHRNA3, CHRM3 | ADRB1 201/4885HTR3E 67/4885HTR3B 75/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.