SCHEMBL3199693

SCHEMBL3199693

CC1=Cc2ccccc2C1CC(=NNc1c(C)cc(C)cc1C)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.36
SMN1; SMN2 Q16637 6/20 0.36
RAB9A P51151 3/20 0.36
NPC1 O15118 2/20 0.36
KMT2A Q03164 5/20 0.35
MEN1 O00255 4/20 0.35
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA4 P22748 2/20 0.33
CA9 Q16790 2/20 0.33
ALDH1A1 P00352 5/20 0.33
TDP1 Q9NUW8 3/20 0.33
KDM4E B2RXH2 2/20 0.33
LMNA P02545 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
GAA P10253 2/20 0.33
HTT P42858 2/20 0.33
THRB P10828 1/20 0.33
HPGD P15428 1/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3202991 0.90 MAPT (0.34) MAPTSMN1; SMN2RAB9ANPC1KMT2A
SCHEMBL3206071 0.86 CA1 (0.40) MAPTSMN1; SMN2RAB9ANPC1KMT2A
SCHEMBL3212484 0.84 MAPT (0.35) MAPTSMN1; SMN2RAB9AKMT2ACA1
SCHEMBL3209522 0.83 LMNA (0.38) MAPTSMN1; SMN2KMT2AMEN1TDP1
SCHEMBL3192712 0.83 MAPT (0.39) MAPTSMN1; SMN2RAB9ANPC1KMT2A
SCHEMBL3204491 0.82 CA1 (0.38) MAPTSMN1; SMN2RAB9ANPC1KMT2A
SCHEMBL3198367 0.81 MAPT (0.32) MAPTSMN1; SMN2CA1CA2CA4
SCHEMBL3204439 0.79 MAPT (0.36) MAPTSMN1; SMN2RAB9ANPC1KMT2A
SCHEMBL3210025 0.77 RAB9A (0.36) SMN1; SMN2RAB9ANPC1KMT2AMEN1
SCHEMBL3199897 0.74 SMN1; SMN2 (0.34) MAPTSMN1; SMN2RAB9AKMT2ACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7732643-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-08 US disclosed
US-7671226-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-02 US disclosed
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME HANAOKA HIDENORI 2010-02-25 US disclosed
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same HANAOKA HIDENORI 2009-02-26 US disclosed
US-7439379-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL CO., LTD. (JP) 2008-10-21 US disclosed
US-20040242410-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-02 US disclosed
EP-1426379-A1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME Sumitomo Chemical Company, Limited (JP) 2004-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same C1R, C1S, AP1M1 MAPT 2641/4885SMN1; SMN2 3599/4885RAB9A 1759/4885
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME C1R, C1S, AP1M1 MAPT 2641/4885SMN1; SMN2 3599/4885RAB9A 1759/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.