SCHEMBL319970

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Trifluoroacetic Acid SCHEMBL14889980	0.94	SCN9A (0.79)	SCN9ACYP2C9SCN5ASCN2BSCN1A
	Pf-05089771 SCHEMBL31060533	0.93	SCN9A (1.00)	SCN9ACYP2C9SCN5ASCN2BSCN1A
	Pf-05089771 SCHEMBL1095065	0.93	SCN9A (1.00)	SCN9ACYP2C9SCN5ASCN2BSCN1A
	Pf-05089771 SCHEMBL29376793	0.93	SCN9A (1.00)	SCN9ACYP2C9SCN5ASCN2BSCN1A
	SCHEMBL17450366	0.91	SCN9A (1.00)	SCN9ACYP2C9SCN5ASCN2BSCN1A
	SCHEMBL321513	0.88	SCN9A (0.89)	SCN9ACYP2C9SCN5ASCN2BSCN1A
	SCHEMBL9924611	0.85	SCN9A (0.85)	SCN9ACYP2C9SCN5ASCN2BSCN1A
	Pf-05089771 SCHEMBL14880153	0.85	SCN9A (0.84)	SCN9ACYP2C9SCN5ASCN2BSCN1A
	SCHEMBL16531041	0.85	SCN9A (1.00)	SCN9ACYP2C9SCN5ASCN2BSCN1A
	SCHEMBL16001939	0.84	SCN9A (0.72)	SCN9ACYP2C9SCN5ASCN2BSCN1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.