Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | GCLC | P48506 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4745489 | 1.00 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2PPARGPPARAPMP22 | |
| SCHEMBL2322915 | 1.00 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2PPARGPPARAPMP22 | |
| SCHEMBL9350162 | 0.83 | HDAC1 (0.43) | ALDH1A1PPARGPPARAPMP22CA2 | |
| SCHEMBL7274699 | 0.83 | HDAC1 (0.43) | ALDH1A1PPARGPPARAPMP22CA2 | |
| SCHEMBL2327532 | 0.83 | HDAC1 (0.43) | ALDH1A1PPARGPPARAPMP22CA2 | |
| SCHEMBL31573244 | 0.82 | SMN1; SMN2 (0.38) | SMN1; SMN2PPARGPPARAGCLCCA2 | |
| SCHEMBL31573243 | 0.82 | SMN1; SMN2 (0.38) | SMN1; SMN2PPARGPPARAGCLCCA2 | |
| SCHEMBL7393830 | 0.82 | SMN1; SMN2 (0.38) | SMN1; SMN2PPARGPPARAGCLCCA2 | |
| SCHEMBL5383912 | 0.80 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2PMP22TDP1 | |
| SCHEMBL5383907 | 0.80 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2PMP22TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1852426-B1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE PPAR-ACTIVATING COMPOUND AND INTERMEDIATE OF THE SAME | KOWA CO (JP) | 2013-11-13 | — | — | EP | disclosed |
| US-7790903-B2 | Process for production of optically active PPAR-activating compound and intermediate of the same | KOWA CO., LTD. (JP) | 2010-09-07 | — | — | US | disclosed |
| US-20080194833-A1 | Process For Production of Optically Active Ppar-Activating Compound and Intermediate of the Same | KOWA CO., LTD. (JP) | 2008-08-14 | — | — | US | disclosed |
| EP-1852426-A1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE PPAR-ACTIVATING COMPOUND AND INTERMEDIATE OF THE SAME | Kowa Company, Ltd. (JP) | 2007-11-07 | — | — | EP | disclosed |
| WO-2000076960-A1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE N-ACYL DERIVATIVES OF METHYL N-(2,6-DIMETHYLPHENYL)-D-ALANINATE | ISAGRO S.P.A. (IT) | 2000-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194833-A1 | Process For Production of Optically Active Ppar-Activating Compound and Intermediate of the Same | PPARA, PPARG, PPARD | ALDH1A1 722/4885SMN1; SMN2 4842/4885PPARG 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.