Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5383912 | 1.00 | ALDH1A1 (0.37) | ALDH1A1TDP1SMN1; SMN2SLC22A6PMP22 | |
| SCHEMBL3199746 | 0.80 | ALDH1A1 (0.39) | ALDH1A1TDP1SMN1; SMN2PMP22 | |
| SCHEMBL4745489 | 0.80 | ALDH1A1 (0.39) | ALDH1A1TDP1SMN1; SMN2PMP22 | |
| SCHEMBL2322915 | 0.80 | ALDH1A1 (0.39) | ALDH1A1TDP1SMN1; SMN2PMP22 | |
| SCHEMBL9567921 | 0.80 | TDP1 (0.39) | TDP1SMN1; SMN2SLC22A6FOLH1 | |
| SCHEMBL6909588 | 0.78 | TDP1 (0.37) | TDP1SMN1; SMN2SLC22A6FOLH1 | |
| SCHEMBL9785113 | 0.77 | ALDH1A1 (0.41) | ALDH1A1ALOX15 | |
| SCHEMBL9785112 | 0.77 | ALDH1A1 (0.41) | ALDH1A1ALOX15 | |
| SCHEMBL8525881 | 0.77 | POLB (0.37) | TDP1SMN1; SMN2SLC22A6FOLH1 | |
| SCHEMBL14498311 | 0.77 | LAP3 (0.43) | ALDH1A1FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187805-B1 | PROCESS FOR PREPARING R-(-)-CARNITINE FROM S-(-)-CHLOROSUCCINIC ACID OR FROM A DERIVATIVE THEREOF | SIGMA TAU IND FARMACEUTI (IT) | 2006-11-29 | — | — | EP | claimed |
| US-20040102645-A1 | Process for preparing R-(-)-carnitin from S-(-)-chlorosuccinic acid or from a derivative thereof | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2004-05-27 | — | — | US | claimed |
| EP-1187805-A1 | PROCESS FOR PREPARING R-(-)-CARNITINE FROM S-(-)-CHLOROSUCCINIC ACID OR FROM A DERIVATIVE THEREOF | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 2002-03-20 | — | — | EP | claimed |
| WO-2000069808-A1 | PROCESS FOR PREPARING R-(-)-CARNITINE FROM S-(-)-CHLOROSUCCINIC ACID OR FROM A DERIVATIVE THEREOF | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2000-11-23 | — | — | WO | claimed |
| US-7247747-B2 | Process for preparing R-(-)carnitine from S-(-)-chlorosuccinic acid or from a derivative thereof | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2007-07-24 | — | — | US | disclosed |
| EP-1187805-B1 | PROCESS FOR PREPARING R-(-)-CARNITINE FROM S-(-)-CHLOROSUCCINIC ACID OR FROM A DERIVATIVE THEREOF | SIGMA TAU IND FARMACEUTI (IT) | 2006-11-29 | — | — | EP | disclosed |
| US-6984739-B2 | Process for preparing R-(−)-carnitin from S-(−)-chlorosuccinic acid or from a derivative thereof | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2006-01-10 | — | — | US | disclosed |
| US-20050245762-A1 | Process for preparing R-(-)carnitine from S-(-)-chlorosuccinic acid or from a derivative thereof | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2005-11-03 | — | — | US | disclosed |
| US-20040102645-A1 | Process for preparing R-(-)-carnitin from S-(-)-chlorosuccinic acid or from a derivative thereof | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2004-05-27 | — | — | US | disclosed |
| US-6677476-B1 | REDUCING HALO- OR SULFONYLOXY-SUCCINIC ACID OR DERIVATIVE WITH SUITABLE REDUCING AGENT, TREATING WITH BASE AND THEN WITH TRIMETHYLAMINE | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2004-01-13 | — | — | US | disclosed |
| EP-1187805-A1 | PROCESS FOR PREPARING R-(-)-CARNITINE FROM S-(-)-CHLOROSUCCINIC ACID OR FROM A DERIVATIVE THEREOF | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 2002-03-20 | — | — | EP | disclosed |
| WO-2000069808-A1 | PROCESS FOR PREPARING R-(-)-CARNITINE FROM S-(-)-CHLOROSUCCINIC ACID OR FROM A DERIVATIVE THEREOF | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2000-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040102645-A1 | Process for preparing R-(-)-carnitin from S-(-)-chlorosuccinic acid or from a derivative thereof | CPT1B, SLC25A20, CPT1A | ALDH1A1 580/4885TDP1 3812/4885SMN1; SMN2 456/4885 |
| US-20050245762-A1 | Process for preparing R-(-)carnitine from S-(-)-chlorosuccinic acid or from a derivative thereof | CPT1B, CRAT, CPT1A | ALDH1A1 986/4885TDP1 4207/4885SMN1; SMN2 371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.