SCHEMBL320003

SCHEMBL320003

CCCO[SiH](CCCCl)OCCC

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.39
TDP1 Q9NUW8 1/20 0.39
ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL600890 0.93 TSHR (0.40) TSHRTDP1ALDH1A1
SCHEMBL31055741 0.88 TSHR (0.43) TSHRTDP1ALDH1A1
SCHEMBL319564 0.85 TSHR (0.30) TSHRTDP1
SCHEMBL706691 0.85
SCHEMBL703383 0.85
SCHEMBL6706823 0.82 TSHR (0.30) TSHR
SCHEMBL1123036 0.82 TSHR (0.30) TSHR
SCHEMBL6708436 0.82 TSHR (0.30) TSHR
SCHEMBL713340 0.82 ADRB2 (0.33) TSHR
SCHEMBL6708448 0.82 TSHR (0.30) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 361 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120202247-A Silane compound and composition containing same 昕特玛私人有限公司 2025-06-24 CN claimed
CN-117924347-A Preparation method of monosulfur organosilane coupling agent 江西宏柏新材料股份有限公司 2024-04-26 CN claimed
CN-117924346-A Multi-sulfur-containing silane coupling agent and preparation method thereof 江西宏柏新材料股份有限公司 2024-04-26 CN claimed
CN-114262302-B Method for synthesizing diisocyanate trimer, catalyst and preparation method thereof 山东新和成维生素有限公司 2023-09-29 CN claimed
CN-115636939-A Preparation method of sulfydryl-containing organic silicon oligomer 广东粤港澳大湾区黄埔材料研究院 2023-01-24 CN claimed
CN-114262302-A Method for synthesizing diisocyanate trimer, catalyst and preparation method thereof 山东新和成维生素有限公司 2022-04-01 CN claimed
CN-109174048-B Silica gel chromatographic packing and preparation method thereof 月旭科技(上海)股份有限公司 2021-12-28 CN claimed
CN-113292591-A Synthesis method and application of 1, 3-bis (isocyanatoalkyl) -1,1,3, 3-tetramethyldisiloxane 唐山三孚新材料有限公司 2021-08-24 CN claimed
CN-111234315-A Sulfur-containing silane coupling agent releasing low-level VOC in use and preparation method thereof 南京曙光精细化工有限公司 2020-06-05 CN claimed
CN-106978067-B A kind of antifog masking liquid, antifog glass window and its manufacturing method 福耀玻璃工业集团股份有限公司 2019-07-05 CN claimed
EP-1534719-B1 METHOD OF MAKING MERCAPTOALKYLALKOXYSILANES DOW CORNING (US) 2006-03-22 EP claimed
EP-1404688-B1 PROCESS FOR THE PREPARATION OF SULFUR-CONTAINING ORGANOSILICON COMPOUNDS DOW CORNING (US) 2005-12-28 EP claimed
CN-1675228-A Method of making mercaptoalkylalkoxysilanes DOW CORNING (US) 2005-09-28 CN claimed
CN-1639173-A Preparation of sulfur-containing organosilicon compounds using a buffered phase transfer catalysis process DOW CORNING (US) 2005-07-13 CN claimed
EP-1534719-A1 METHOD OF MAKING MERCAPTOALKYLALKOXYSILANES Dow Corning Corporation (US) 2005-06-01 EP claimed
CN-1522261-A Process for preparing sulfur-containing organosilicon compounds 2004-08-18 CN claimed
WO-2004016629-A1 METHOD OF MAKING MERCAPTOALKYLALKOXYSILANES DOW CORNING CORPORATION (US) 2004-02-26 WO claimed
US-6680398-B1 REACTING CHLOROPROPYLTRIETHOXYSILANE WITH SODIUM HYDROSULFIDE IN THE PRESENCE OF BUFFERS AND PHASE TRANSFER AGENTS AS CATALYST, TO FORM MERCAPTOPROPYLTRIETHOXYSILANE; BY-PRODUCT INHIBITION; DEHALOGENATION DOW CORNING CORPORATION 2004-01-20 US claimed
US-5834536-A REACTING HALOGENATED ALKYL SILANE WITH INORGANIC POLYSULFIDE IN PRESENCE OF WATER AND FILLER(CARRIER) FIBERS OR PARTICLES, THEN DRYING BEFORE MIXING INTO RUBBER; FOR HEAT RESISTANT TIRES HAVING LOW ROLLING RESISTANCE BAYER AG (DE) 1998-11-10 US claimed
US-5446181-A Method and apparatus for preparing 3-[N-(2-aminoethyl)]aminopropylalkoxysilane SHIN-ETSU CHEMICAL CO., LTD. (JP) 1995-08-29 US claimed