Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | BRAF | P15056 | 2/20 | 0.33 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.32 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.31 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25791 | 0.79 | HTT (0.40) | HTTALDH1A1KDM4EPKMPOLB | |
| SCHEMBL25790 | 0.79 | HTT (0.40) | HTTALDH1A1KDM4EPKMPOLB | |
| SCHEMBL1466994 | 0.73 | CASP1 (0.49) | ALDH1A1KDM4EL3MBTL1KMT2ALMNA | |
| SCHEMBL1466993 | 0.73 | CASP1 (0.49) | ALDH1A1KDM4EL3MBTL1KMT2ALMNA | |
| SCHEMBL11310062 | 0.69 | SMN1; SMN2 (0.50) | HTTALDH1A1KDM4EGAAPOLB | |
| SCHEMBL1468252 | 0.68 | MAOA (0.56) | ALDH1A1KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL1468250 | 0.68 | MAOA (0.56) | ALDH1A1KDM4EL3MBTL1MEN1KMT2A | |
| SCHEMBL1814402 | 0.67 | HTT (0.57) | HTTL3MBTL1BRAFMAPK3MAPK1 | |
| SCHEMBL1814405 | 0.67 | HTT (0.57) | HTTL3MBTL1BRAFMAPK3MAPK1 | |
| SCHEMBL1814401 | 0.67 | HTT (0.57) | HTTL3MBTL1BRAFMAPK3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012026403-A1 | CONDENSED RING COMPOUND | 日本曹達株式会社 (JP) | 2012-03-01 | — | — | WO | disclosed |