SCHEMBL3200296

SCHEMBL3200296

CCCCNC(C)c1ccccc1C1=C(C)C=CC1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
APAF1 O14727 1/20 0.36
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33
BCHE P06276 1/20 0.33
ACHE P22303 1/20 0.33
SCN8A Q9UQD0 1/20 0.32
IDO1 P14902 2/20 0.31
ADRA2C P18825 2/20 0.31
SLC6A2 P23975 2/20 0.31
HTR2C P28335 2/20 0.31
SLC6A4 P31645 2/20 0.31
OPRM1 P35372 2/20 0.31
DRD3 P35462 2/20 0.31
CASR P41180 2/20 0.31
MLNR O43193 1/20 0.31
ABCB11 O95342 1/20 0.31
ADRB1 P08588 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
CYP2D6 P10635 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3211172 0.82 ALDH1A1 (0.33) ALDH1A1APAF1POLBMAPTBCHE
SCHEMBL3860946 0.81 APAF1 (0.34) ALDH1A1APAF1BCHEACHE
SCHEMBL3210918 0.81 ALDH1A1 (0.38) ALDH1A1APAF1POLBMAPTBCHE
Hydrochloric Acid SCHEMBL3263040 0.80 APAF1 (0.33) ALDH1A1APAF1BCHEACHE
SCHEMBL3203862 0.79 ALDH1A1 (0.33) ALDH1A1APAF1POLBMAPTBCHE
SCHEMBL3200429 0.79 ALDH1A1 (0.33) ALDH1A1APAF1POLBMAPTBCHE
SCHEMBL3202751 0.76 CHRM2 (0.42) BCHEACHESCN8ACYP2D6CHRM1
SCHEMBL3215805 0.76 BCHE (0.35) ALDH1A1APAF1POLBMAPTBCHE
SCHEMBL3202398 0.75 CACNA1F (0.31) SLC6A4CHRM1CHRM3HRH1SLC6A3
SCHEMBL3207600 0.75 TDP1 (0.42) ALDH1A1HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7732643-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-08 US disclosed
US-7671226-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-02 US disclosed
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME HANAOKA HIDENORI 2010-02-25 US disclosed
EP-1426379-B1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME SUMITOMO CHEMICAL CO (JP) 2009-11-11 EP disclosed
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same HANAOKA HIDENORI 2009-02-26 US disclosed
US-7439379-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL CO., LTD. (JP) 2008-10-21 US disclosed
US-20040242410-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-02 US disclosed
EP-1426379-A1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME Sumitomo Chemical Company, Limited (JP) 2004-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same C1R, C1S, AP1M1 ALDH1A1 1229/4885APAF1 3003/4885POLB 964/4885
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME C1R, C1S, AP1M1 ALDH1A1 1229/4885APAF1 3003/4885POLB 964/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.