Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3195763 | 1.00 | SMN1; SMN2 (0.33) | SMN1; SMN2CYP1A2MAPK1KDM4EMEN1 | |
| SCHEMBL3197559 | 0.98 | SMN1; SMN2 (0.33) | SMN1; SMN2CYP1A2MAPK1KDM4EMEN1 | |
| SCHEMBL3196836 | 0.92 | HRH3 (0.36) | SMN1; SMN2CYP1A2MAPK1MEN1KMT2A | |
| SCHEMBL3207388 | 0.92 | HRH3 (0.36) | SMN1; SMN2CYP1A2MAPK1MEN1KMT2A | |
| SCHEMBL3214473 | 0.92 | MEN1 (0.32) | SMN1; SMN2CYP1A2MAPK1MEN1KMT2A | |
| SCHEMBL3214312 | 0.92 | MEN1 (0.32) | SMN1; SMN2CYP1A2MAPK1MEN1KMT2A | |
| SCHEMBL3210574 | 0.90 | HRH3 (0.34) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL3199033 | 0.90 | KDM5A (0.31) | L3MBTL1 | |
| SCHEMBL3199804 | 0.86 | ITGB3 (0.32) | SMN1; SMN2CYP1A2MAPK1MEN1KMT2A | |
| SCHEMBL3187141 | 0.86 | ITGB3 (0.32) | SMN1; SMN2CYP1A2MAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8937090-B2 | Parakeratosis inhibitor, pore-shrinking agent and external composition for skin | SHISEIDO COMPANY, LTD. (JP) | 2015-01-20 | — | — | US | disclosed |
| US-20120232111-A1 | Parakeratosis inhibitor, pore -shrinking agent and external compositon for skin | SHISEIDO COMPANY, LTD. (JP) | 2012-09-13 | — | — | US | disclosed |
| US-20120165409-A1 | WRINKLE-IMPROVING AGENT | SHISEIDO COMPANY, LTD. (JP) | 2012-06-28 | — | — | US | disclosed |
| US-20100035881-A1 | WRINKLE-IMPROVING AGENT | SHISEIDO COMPANY, LTD. (JP) | 2010-02-11 | — | — | US | disclosed |
| EP-1941861-A1 | WRINKLE-IMPROVING AGENT | Shiseido Company, Limited (JP) | 2008-07-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035881-A1 | WRINKLE-IMPROVING AGENT | AAAS, GLA, COL14A1 | SMN1; SMN2 24/4885CYP1A2 3833/4885MAPK1 2330/4885 |
| US-20120232111-A1 | Parakeratosis inhibitor, pore -shrinking agent and external compositon for skin | CUTA, AAAS, NUP160 | SMN1; SMN2 3451/4885CYP1A2 3980/4885MAPK1 2393/4885 |
| US-20120165409-A1 | WRINKLE-IMPROVING AGENT | AAAS, GLA, COL14A1 | SMN1; SMN2 29/4885CYP1A2 3658/4885MAPK1 2010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.