Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Glycerin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycerin SCHEMBL22720645 | 1.00 | FFAR3 (0.53) | FFAR3LMNAALDH1A1SLC22A6TDP1 | |
| Glycerin SCHEMBL1685705 | 1.00 | FFAR3 (0.53) | FFAR3LMNAALDH1A1SLC22A6TDP1 | |
| Glycerin SCHEMBL27744275 | 1.00 | FFAR3 (0.53) | FFAR3LMNAALDH1A1SLC22A6TDP1 | |
| Glycerin SCHEMBL1685702 | 1.00 | FFAR3 (0.53) | FFAR3LMNAALDH1A1SLC22A6TDP1 | |
| Glycerin SCHEMBL30494639 | 0.95 | FFAR3 (0.59) | FFAR3LMNAALDH1A1SLC22A6OR51E2 | |
| Glycerin SCHEMBL78123 | 0.95 | FFAR3 (0.59) | FFAR3LMNAALDH1A1SLC22A6OR51E2 | |
| Glycerin SCHEMBL274755 | 0.95 | FFAR3 (0.59) | FFAR3LMNAALDH1A1SLC22A6OR51E2 | |
| Glycerin SCHEMBL8830214 | 0.95 | FFAR3 (0.59) | FFAR3LMNAALDH1A1SLC22A6OR51E2 | |
| Glycerin SCHEMBL30749460 | 0.95 | FFAR3 (0.59) | FFAR3LMNAALDH1A1SLC22A6OR51E2 | |
| Oxalic Acid SCHEMBL27721607 | 0.90 | FFAR3 (0.53) | FFAR3LMNAALDH1A1SLC22A6OR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100035997-A1 | KIT FOR APPLYING A POLYMERIZABLE ADHESIVE COMPOSITION TO TISSUES | BROADLEY KENNETH N | 2010-02-11 | — | — | US | disclosed |
| US-20100029978-A1 | RAPIDLY CURING CYANOACRYLATES AS ADHESIVES | SWORDS NOELEEN | 2010-02-04 | — | — | US | disclosed |
| CN-100554357-C | Gap-bridging cyanoacrylate adhesive | HENKEL KGAA (DE) | 2009-10-28 | — | — | CN | disclosed |
| CN-1910246-A | Gap-bridging cyanoacrylate adhesive | HENKEL KGAA (DE) | 2007-02-07 | — | — | CN | disclosed |
| US-20060241226-A1 | GAP-FILLING CYANOACRYLATE ADHESIVE | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2006-10-26 | — | — | US | disclosed |
| US-6617385-B1 | Alkylene biscyanoacrylate; addition polymer; ester plasticizer | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2003-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035997-A1 | KIT FOR APPLYING A POLYMERIZABLE ADHESIVE COMPOSITION TO TISSUES | KIT, TEKT1, CUTA | FFAR3 1843/4885LMNA 3618/4885ALDH1A1 740/4885 |
| US-20100029978-A1 | RAPIDLY CURING CYANOACRYLATES AS ADHESIVES | ICAM1, ITGA1, ITGA5 | FFAR3 2081/4885LMNA 1838/4885ALDH1A1 386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.