Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | GLA | P06280 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | CASP7 | P55210 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15101764 | 1.00 | SRC (0.46) | SRCKDM4EALDH1A1HPGDGLA | |
| SCHEMBL3675107 | 0.84 | SRC (0.46) | SRCKDM4EALDH1A1HPGDGLA | |
| SCHEMBL5675497 | 0.83 | SRC (0.51) | SRCKDM4EALDH1A1HPGDGLA | |
| SCHEMBL20522377 | 0.82 | SRC (0.46) | SRCKDM4EALDH1A1HPGDGLA | |
| SCHEMBL3675110 | 0.82 | SRC (0.46) | SRCKDM4EALDH1A1HPGDGLA | |
| SCHEMBL1978750 | 0.79 | SRC (0.66) | SRCKDM4EALDH1A1HPGDGLA | |
| SCHEMBL8679670 | 0.79 | SRC (0.53) | SRCKDM4EALDH1A1HPGDGLA | |
| SCHEMBL3275289 | 0.77 | SRC (0.49) | SRCKDM4EALDH1A1HPGDGLA | |
| SCHEMBL7586984 | 0.77 | SRC (0.49) | SRCKDM4EALDH1A1HPGDGLA | |
| SCHEMBL10783437 | 0.77 | SRC (0.47) | SRCKDM4EALDH1A1HPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8486650-B2 | Method of detecting serum gamma-glutamyl transferase isoforms in a biological fluid | UNIVERSITA' DI PISA (IT) | 2013-07-16 | — | — | US | claimed |
| US-20100227351-A1 | METHOD OF DETECTING AND SEPARATING SERUM GAMMA-GLUTAMYL TRANSFERASE (GGT) ISOFORMS IN A SAMPLE OF BIOLOGICAL FLUID AND THE ENZYME ISOFORMS THEREBY OBTAINED | UNIVERSITA' DI PISA (IT) | 2010-09-09 | — | — | US | claimed |
| EP-2167678-A2 | A METHOD OF DETECTING AND SEPARATING SERUM GAMMA-GLUTAMYL TRANSFERASE (GGT) ISOFORMS IN A SAMPLE OF BIOLOGICAL FLUID AND THE ENZYME ISOFORMS THEREBY OBTAINED | Universita' Di Pisa (IT) | 2010-03-31 | — | — | EP | claimed |
| WO-2009001290-A2 | A METHOD OF DETECTING AND SEPARATING SERUM GAMMA-GLUTAMYL TRANSFERASE (GGT) ISOFORMS IN A SAMPLE OF BIOLOGICAL FLUID AND THE ENZYME ISOFORMS THEREBY OBTAINED | UNIVERSITA' DI PISA (IT) | 2008-12-31 | — | — | WO | claimed |
| EP-1361885-B1 | USE OF GAMMA-GT INHIBITORS FOR THE TREATMENT OF CHRONIC DEGENERATIVE DISEASES | GTX PHARMACEUTICALS GMBH (DE) | 2008-04-16 | — | — | EP | claimed |
| US-20040115284-A1 | Use of gamma-GT inhibitors for the treatment of degenerative diseases | GTX PHARMACEUTICALS GMBH (DE) | 2004-06-17 | — | — | US | claimed |
| EP-1361885-A1 | USE OF $G(G)-GT INHIBITORS FOR THE TREATMENT OF DEGENERATIVE DISEASES | GTX Pharmaceuticals GmbH (DE) | 2003-11-19 | — | — | EP | claimed |
| WO-2002066047-A1 | USE OF $G(G)-GT INHIBITORS FOR THE TREATMENT OF DEGENERATIVE DISEASES | GTX PHARMACEUTICALS GMBH (DE) | 2002-08-29 | — | — | WO | claimed |
| US-8486650-B2 | Method of detecting serum gamma-glutamyl transferase isoforms in a biological fluid | UNIVERSITA' DI PISA (IT) | 2013-07-16 | — | — | US | disclosed |
| US-20100227351-A1 | METHOD OF DETECTING AND SEPARATING SERUM GAMMA-GLUTAMYL TRANSFERASE (GGT) ISOFORMS IN A SAMPLE OF BIOLOGICAL FLUID AND THE ENZYME ISOFORMS THEREBY OBTAINED | UNIVERSITA' DI PISA (IT) | 2010-09-09 | — | — | US | disclosed |
| CN-101730747-A | The method and the thus obtained enzyme isoforms of serum gamma glutamyltransferase (GGT) isotype in detection and the separating bio fluid sample | UNIV PISA | 2010-06-09 | — | — | CN | disclosed |
| EP-2167678-A2 | A METHOD OF DETECTING AND SEPARATING SERUM GAMMA-GLUTAMYL TRANSFERASE (GGT) ISOFORMS IN A SAMPLE OF BIOLOGICAL FLUID AND THE ENZYME ISOFORMS THEREBY OBTAINED | Universita' Di Pisa (IT) | 2010-03-31 | — | — | EP | disclosed |
| WO-2009001290-A2 | A METHOD OF DETECTING AND SEPARATING SERUM GAMMA-GLUTAMYL TRANSFERASE (GGT) ISOFORMS IN A SAMPLE OF BIOLOGICAL FLUID AND THE ENZYME ISOFORMS THEREBY OBTAINED | UNIVERSITA' DI PISA (IT) | 2008-12-31 | — | — | WO | disclosed |
| EP-1361885-B1 | USE OF GAMMA-GT INHIBITORS FOR THE TREATMENT OF CHRONIC DEGENERATIVE DISEASES | GTX PHARMACEUTICALS GMBH (DE) | 2008-04-16 | — | — | EP | disclosed |
| US-20040115284-A1 | Use of gamma-GT inhibitors for the treatment of degenerative diseases | GTX PHARMACEUTICALS GMBH (DE) | 2004-06-17 | — | — | US | disclosed |
| EP-1361885-A1 | USE OF $G(G)-GT INHIBITORS FOR THE TREATMENT OF DEGENERATIVE DISEASES | GTX Pharmaceuticals GmbH (DE) | 2003-11-19 | — | — | EP | disclosed |
| WO-2002066047-A1 | USE OF $G(G)-GT INHIBITORS FOR THE TREATMENT OF DEGENERATIVE DISEASES | GTX PHARMACEUTICALS GMBH (DE) | 2002-08-29 | — | — | WO | disclosed |
| US-5780247-A | FORMING COMPLEXES WITH ONE OR MORE AFFINITY SUBSTANCES; SEPARATING THE COMPLEXES BY USING HIGH PRESSURE LIQUID CHROMATOGRAPHY | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1998-07-14 | — | — | US | disclosed |
| EP-0441470-B1 | Process for separating and measuring trace components | WAKO PURE CHEM IND LTD (JP) | 1995-12-20 | — | — | EP | disclosed |
| EP-0441470-A2 | Process for separating and measuring trace components | WAKO PURE CHEMICAL INDUSTRIES LTD (JP) | 1991-08-14 | — | — | EP | disclosed |