Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3217097 | 0.90 | HRH4 (0.34) | HRH4 | |
| SCHEMBL3255495 | 0.85 | PDE4B (0.35) | — | |
| SCHEMBL3192323 | 0.83 | HRH4 (0.33) | HRH4 | |
| SCHEMBL3194668 | 0.83 | RORC (0.35) | HRH4TRPM8 | |
| SCHEMBL3203145 | 0.82 | PDE4D (0.37) | HRH4TRPM8 | |
| SCHEMBL3204654 | 0.82 | HRH4 (0.33) | HRH4TRPM8 | |
| SCHEMBL3128295 | 0.82 | PDE4B (0.42) | — | |
| SCHEMBL3193291 | 0.81 | PCSK9 (0.39) | HRH4TRPM8 | |
| SCHEMBL3205112 | 0.80 | HRH4 (0.38) | HRH4TRPM8 | |
| SCHEMBL3122844 | 0.80 | PDE4A (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029689-A1 | PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2010-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029689-A1 | PHOSPHODIESTERASE 4 INHIBITORS | PDE4A, PDE4B, PDE3B | HRH4 442/4885TRPM8 3474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.