SCHEMBL3202252

SCHEMBL3202252

COC(=O)Cn1c2ccccc2c2ccccc21

nearest known ligand 0.69

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.69
SMN1; SMN2 Q16637 2/20 0.69
KMT2A Q03164 3/20 0.64
TSHR P16473 2/20 0.58
GAA P10253 1/20 0.56
TSPO P30536 1/20 0.56
ALDH1A1 P00352 4/20 0.55
HSD17B10 Q99714 3/20 0.55
HPGD P15428 2/20 0.54
LMNA P02545 1/20 0.54
HTT P42858 1/20 0.54
POLB P06746 1/20 0.54
MEN1 O00255 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
GLA P06280 1/20 0.51
MAPT P10636 1/20 0.51
NPC1 O15118 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29246468 0.87 KMT2A (0.55) KDM4ESMN1; SMN2KMT2ATSHRGAA
SCHEMBL10152245 0.87 KDM4E (0.60) KDM4ESMN1; SMN2KMT2ATSHRGAA
SCHEMBL9141483 0.87 KDM4E (0.54) KDM4ESMN1; SMN2KMT2ATSHRGAA
SCHEMBL11605995 0.85 KDM4E (0.59) KDM4ESMN1; SMN2KMT2ATSHRGAA
SCHEMBL1757397 0.82 KDM4E (0.56) KDM4ESMN1; SMN2KMT2ATSHRGAA
SCHEMBL29540705 0.82 KDM4E (0.71) KDM4EKMT2ATSHRTSPOALDH1A1
SCHEMBL1004258 0.82 FABP4 (0.64) KDM4ESMN1; SMN2TSHRALDH1A1HPGD
SCHEMBL151122 0.82 KDM4E (0.71) KDM4EKMT2ATSHRTSPOALDH1A1
SCHEMBL31367787 0.82 FABP4 (0.64) KDM4ESMN1; SMN2TSHRALDH1A1HPGD
SCHEMBL11811656 0.81 KDM4E (0.80) KDM4ESMN1; SMN2KMT2ATSHRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1840650-B1 Positive type radiation-sensitive resin composition JSR CORP (JP) 2009-03-18 EP claimed
EP-1840650-A1 Positive type radiation-sensitive resin composition JSR Corporation (JP) 2007-10-03 EP claimed
US-20060223010-A1 Positive type radiation-sensitive resin composition JSR CORPORATION (JP) 2006-10-05 US claimed
US-8206888-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2012-06-26 US disclosed
US-20100028800-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR CORPORATION (JP) 2010-02-04 US disclosed
EP-1840650-B1 Positive type radiation-sensitive resin composition JSR CORP (JP) 2009-03-18 EP disclosed
US-7488566-B2 Positive type radiation-sensitive resin composition JSR CORPORATION (JP) 2009-02-10 US disclosed
EP-1640804-B1 Positive-tone radiation-sensitive resin composition JSR CORP (JP) 2008-11-19 EP disclosed
EP-1953593-A1 RADIATION-SENSITIVE RESIN COMPOSITION JSR Corporation (JP) 2008-08-06 EP disclosed
US-7335457-B2 Positive-tone radiation-sensitive resin composition JSR CORPORATION (JP) 2008-02-26 US disclosed
EP-1840650-A1 Positive type radiation-sensitive resin composition JSR Corporation (JP) 2007-10-03 EP disclosed
US-20060223010-A1 Positive type radiation-sensitive resin composition JSR CORPORATION (JP) 2006-10-05 US disclosed
US-20060078821-A1 A caroboxyalkylanthracene based compound, a hydroxy or alkoxystyrene polymer, and a sulfonimide compound as photoacid generator; low sublimation properties and excellent compatibility with other components; exhibits optimum controllability of radiation transmittance; microfabrication JSR CORPORATION (JP) 2006-04-13 US disclosed
EP-1640804-A2 Positive-tone radiation-sensitive resin composition JSR Corporation (JP) 2006-03-29 EP disclosed