Ademetionine

Ademetionine

SCHEMBL3202538

C[S+](CC[C@@H](N)C(=O)O)C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 5/20 1.00
AMD1 P17707 4/20 1.00
PCMT1 P22061 3/20 0.87
PRMT5 O14744 3/20 0.87
PRMT1 Q99873 3/20 0.87
NSD3 Q9BZ95 2/20 0.87
PRMT3 O60678 2/20 0.87
PNMT P11086 2/20 0.87
PRMT6 Q96LA8 2/20 0.87
WDR77 Q9BQA1 2/20 0.87
PRMT7 Q9NVM4 2/20 0.87
ADORA3 P0DMS8 1/20 0.87
KDR P35968 1/20 0.87
PRMT8 Q9NR22 1/20 0.87
NNMT P40261 3/20 0.72
DOT1L Q8TEK3 5/20 0.71
NSD2 O96028 3/20 0.71
SETD7 Q8WTS6 3/20 0.71
EHMT2 Q96KQ7 3/20 0.71
TRDMT1 O14717 2/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ademetionine SCHEMBL13033865 1.00 CARM1 (1.00) CARM1AMD1PCMT1PRMT5PRMT1
Ademetionine SCHEMBL600368 1.00 CARM1 (1.00) CARM1AMD1PCMT1PRMT5PRMT1
Ademetionine SCHEMBL66767 1.00 CARM1 (1.00) CARM1AMD1PCMT1PRMT5PRMT1
Ademetionine SCHEMBL2007787 1.00 CARM1 (1.00) CARM1AMD1PCMT1PRMT5PRMT1
Ademetionine SCHEMBL599664 1.00 CARM1 (1.00) CARM1AMD1PCMT1PRMT5PRMT1
Ademetionine SCHEMBL4164615 1.00 CARM1 (1.00) CARM1AMD1PCMT1PRMT5PRMT1
Ademetionine SCHEMBL55479 1.00 CARM1 (1.00) CARM1AMD1PCMT1PRMT5PRMT1
Ademetionine SCHEMBL7810282 1.00 CARM1 (1.00) CARM1AMD1PCMT1PRMT5PRMT1
Ademetionine SCHEMBL59293 1.00 CARM1 (1.00) CARM1AMD1PCMT1PRMT5PRMT1
Ademetionine SCHEMBL9518716 1.00 CARM1 (1.00) CARM1AMD1PCMT1PRMT5PRMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120005956-A Method for biosynthesis of allantoin by using D-xylose 福州大学 2025-05-16 CN claimed
EP-4359560-B1 MULTIRESIDUAL METHOD FOR DETECTING AND/OR QUANTIFYING AMINO ACIDS, ORGANIC ACIDS AND/OR MODIFIED NUCLEOTIDES BY MEANS OF HILIC CHROMATOGRAPHIC SEPARATION AND MS/MS CRESCENDO CARE S R L (IT) 2025-05-07 EP claimed
EP-3488006-B1 MATERIALS AND METHODS UTILIZING BIOTIN PRODUCING MUTANT HOSTS FOR THE PRODUCTION OF 7-CARBON CHEMICALS INVISTA TEXTILES UK LTD (GB) 2023-06-07 EP claimed
CN-110857315-A Polypeptide medicine and derivative for treating tumor and use method thereof 许洋 2020-03-03 CN claimed
US-9365817-B2 Dried and/or microencapsulated Saccharomyces cerevisiae cells with a high content of (s)-(+)-s-adenosyl-l-methionine, process for their preparation, and compositons containing said cells GNOSIS S.P.A. (IT) 2016-06-14 US claimed
EP-1731596-B1 Dried, freeze-dried and/or microencapsulated Saccharomyces cerevisiae cells with a high content of (S)-(+)-S-adenosyl-L-methionine GNOSIS SPA (IT) 2013-03-27 EP claimed
US-6958233-B2 Process for the preparation of pharmaceutically acceptable salts of (R,S)-S-adenosyl-L-methionine CHEMENTECNO S.R.L. (IT) 2005-10-25 US claimed
EP-4138828-B1 ORAL COMPOSITION CONTAINING S-ADENOSYLMETHIONINE (SAMe) AND A MIXTURE OF PROBIOTICS AND USE THEREOF MONTEFARMACO OTC S P A (IT) 2025-10-01 EP disclosed
CN-120005956-A Method for biosynthesis of allantoin by using D-xylose 福州大学 2025-05-16 CN disclosed
CN-120005956-A Method for biosynthesis of allantoin by using D-xylose 福州大学 2025-05-16 CN disclosed
CN-119082070-A High-activity and heat-stable methionine adenosine transferase mutant and application thereof 武汉启瑞药业有限公司 2024-12-06 CN disclosed
EP-2968386-C0 IMMUNOASSAY OF S-ADENOSYLMETHIONINE USING ANALOGS THEREOF AND PERSONALIZED THERAPEUTICS HAO XIUJUAN (US) 2024-05-08 EP disclosed
EP-2968386-B1 IMMUNOASSAY OF S-ADENOSYLMETHIONINE USING ANALOGS THEREOF AND PERSONALIZED THERAPEUTICS HAO XIUJUAN (US) 2024-05-08 EP disclosed
WO-2006131382-A1 DRIED AND/OR MICROENCAPSULATED SACCHAROMYCES CEREVISIAE CELLS WITH A HIGH CONTENT OF (S)-(+)-S-ADENOSYL-L-METHIONINE, PROCESS FOR THEIR PREPARATION, AND COMPOSITIONS CONTAINING SAID CELLS GNOSIS S.P.A. (IT) 2006-12-14 WO disclosed
EP-1731596-A1 Dried, freeze-dried and/or microencapsulated Saccharomyces cerevisiae cells with a high content of (S)-(+)-S-adenosyl-L-methionine Gnosis S.p.A. (IT) 2006-12-13 EP disclosed
US-6958233-B2 Process for the preparation of pharmaceutically acceptable salts of (R,S)-S-adenosyl-L-methionine CHEMENTECNO S.R.L. (IT) 2005-10-25 US disclosed
US-6958233-B2 Process for the preparation of pharmaceutically acceptable salts of (R,S)-S-adenosyl-L-methionine CHEMENTECNO S.R.L. (IT) 2005-10-25 US disclosed
US-6686172-B2 Method of measuring total homocysteine AZWELL, INC. (JP) 2004-02-03 US disclosed
EP-1295947-A1 METHOD OF MEASURING TOTAL HOMOCYSTEINE Azwell Inc. (JP) 2003-03-26 EP disclosed
US-20020123088-A1 Method of measuring total homocysteine ALFRESA PHARMA CORPORATION (JP) 2002-09-05 US disclosed