Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 5/20 | 1.00 |
| ▸ | AMD1 | P17707 | 4/20 | 1.00 |
| ▸ | PCMT1 | P22061 | 3/20 | 0.87 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.87 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.87 |
| ▸ | NSD3 | Q9BZ95 | 2/20 | 0.87 |
| ▸ | PRMT3 | O60678 | 2/20 | 0.87 |
| ▸ | PNMT | P11086 | 2/20 | 0.87 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.87 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.87 |
| ▸ | PRMT7 | Q9NVM4 | 2/20 | 0.87 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.87 |
| ▸ | KDR | P35968 | 1/20 | 0.87 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.87 |
| ▸ | NNMT | P40261 | 3/20 | 0.72 |
| ▸ | DOT1L | Q8TEK3 | 5/20 | 0.71 |
| ▸ | NSD2 | O96028 | 3/20 | 0.71 |
| ▸ | SETD7 | Q8WTS6 | 3/20 | 0.71 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.71 |
| ▸ | TRDMT1 | O14717 | 2/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ademetionine SCHEMBL13033865 | 1.00 | CARM1 (1.00) | CARM1AMD1PCMT1PRMT5PRMT1 | |
| Ademetionine SCHEMBL66767 | 1.00 | CARM1 (1.00) | CARM1AMD1PCMT1PRMT5PRMT1 | |
| Ademetionine SCHEMBL2007787 | 1.00 | CARM1 (1.00) | CARM1AMD1PCMT1PRMT5PRMT1 | |
| Ademetionine SCHEMBL599664 | 1.00 | CARM1 (1.00) | CARM1AMD1PCMT1PRMT5PRMT1 | |
| Ademetionine SCHEMBL4164615 | 1.00 | CARM1 (1.00) | CARM1AMD1PCMT1PRMT5PRMT1 | |
| Ademetionine SCHEMBL55479 | 1.00 | CARM1 (1.00) | CARM1AMD1PCMT1PRMT5PRMT1 | |
| Ademetionine SCHEMBL7810282 | 1.00 | CARM1 (1.00) | CARM1AMD1PCMT1PRMT5PRMT1 | |
| Ademetionine SCHEMBL59293 | 1.00 | CARM1 (1.00) | CARM1AMD1PCMT1PRMT5PRMT1 | |
| Ademetionine SCHEMBL3202538 | 1.00 | CARM1 (1.00) | CARM1AMD1PCMT1PRMT5PRMT1 | |
| Ademetionine SCHEMBL9518716 | 1.00 | CARM1 (1.00) | CARM1AMD1PCMT1PRMT5PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040923-A1 | STABLE S-ADENOSYL-L-METHIONINE | HEBERT ROLLAND F (US) | 2012-02-16 | — | — | US | claimed |
| US-20100004191-A1 | Compositions of S-adenosyl-L-methionine. | HEBERT SAM-E LLC | 2010-01-07 | — | — | US | claimed |
| US-20090012036-A1 | Stable S-adenosyl-L-methionine | HEBERT SAM-E LLC | 2009-01-08 | — | — | US | claimed |
| US-7387796-B2 | Stable compositions of S-adenosyl-l-methionine with dextran | HEBERT SAM-E LLC | 2008-06-17 | — | — | US | claimed |
| US-20060127506-A1 | Compositions of S-adenosyl-L-methionine | HEBERT SAM-E LLC | 2006-06-15 | — | — | US | claimed |
| US-20040063660-A1 | Diasteriomers of S-adenosyl-l-methionine and uses thereof | HEBERT ROLLAND F (US) | 2004-04-01 | — | — | US | claimed |
| US-20030144244-A1 | Stable compositions of S-adenosyl-l-methionine with dextran | HEBERT SAM-E LLC | 2003-07-31 | — | — | US | claimed |
| US-20020025926-A1 | Enantiomers of S-adenosyl-l-methionine | HEBERT ROLLAND F (US) | 2002-02-28 | — | — | US | claimed |
| EP-3071191-B1 | SLOW-RELEASE SOLID ORAL COMPOSITIONS | GNOSIS SPA (IT) | 2022-01-05 | — | — | EP | disclosed |
| US-10702482-B2 | Slow-release solid oral compositions | GNOSIS SPA (IT) | 2020-07-07 | — | — | US | disclosed |
| EP-2945959-B1 | STABLE INDOLE-3-PROPIONATE SALTS OF S-ADENOSYL-L-METHIONINE | HEBERT SAM E LLC (US) | 2020-05-13 | — | — | EP | disclosed |
| US-9534010-B2 | Stable indole-3-propionate salts of S-adenosyl-L-methionine | HEBERT SAM-E LLC | 2017-01-03 | — | — | US | disclosed |
| US-20160287519-A1 | SLOW-RELEASE SOLID ORAL COMPOSITIONS | GNOSIS SPA (IT) | 2016-10-06 | — | — | US | disclosed |
| US-20160271063-A1 | STERILE S-ADENOSYL METHIONINE WITH A HIGH CONTENT OF ACTIVE ISOMER FOR INJECTABLE SOLUTIONS, AND PROCEDURE FOR OBTAINING IT | GNOSIS S.P.A. (IT) | 2016-09-22 | — | — | US | disclosed |
| US-6958233-B2 | Process for the preparation of pharmaceutically acceptable salts of (R,S)-S-adenosyl-L-methionine | CHEMENTECNO S.R.L. (IT) | 2005-10-25 | — | — | US | disclosed |
| US-6958233-B2 | Process for the preparation of pharmaceutically acceptable salts of (R,S)-S-adenosyl-L-methionine | CHEMENTECNO S.R.L. (IT) | 2005-10-25 | — | — | US | disclosed |
| US-20040063660-A1 | Diasteriomers of S-adenosyl-l-methionine and uses thereof | HEBERT ROLLAND F (US) | 2004-04-01 | — | — | US | disclosed |
| US-20040063660-A1 | Diasteriomers of S-adenosyl-l-methionine and uses thereof | HEBERT ROLLAND F (US) | 2004-04-01 | — | — | US | disclosed |
| US-20030144244-A1 | Stable compositions of S-adenosyl-l-methionine with dextran | HEBERT SAM-E LLC | 2003-07-31 | — | — | US | disclosed |
| US-20020173012-A1 | Process for the preparation of pharmaceutically acceptable salts of (R,S)-S-adenosyl-L-methionine | BERNA MARCO (IT) | 2002-11-21 | — | — | US | disclosed |