Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 8/20 | 0.69 |
| ▸ | ANPEP | P15144 | 1/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.55 |
| ▸ | CTSC | P53634 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8894290 | 0.97 | CTSD (0.66) | CTSDANPEPOPRK1CTSC | |
| SCHEMBL29944413 | 0.92 | CTSD (0.61) | CTSDANPEPOPRK1CTSC | |
| SCHEMBL29732072 | 0.92 | CTSD (0.61) | CTSDANPEPOPRK1CTSC | |
| SCHEMBL30051660 | 0.88 | CTSD (0.55) | CTSDCTSC | |
| SCHEMBL28256394 | 0.86 | CTSD (0.68) | CTSDOPRK1CTSC | |
| SCHEMBL26891675 | 0.85 | LTA4H (0.56) | CTSDANPEPCTSC | |
| SCHEMBL29352698 | 0.85 | LTA4H (0.56) | CTSDANPEPCTSC | |
| SCHEMBL29732222 | 0.85 | LTA4H (0.56) | CTSDANPEPCTSC | |
| SCHEMBL9485864 | 0.85 | CTSC (0.57) | CTSDCTSC | |
| SCHEMBL4434431 | 0.85 | CTSC (0.57) | CTSDCTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389764-B2 | Urea and sulfamide derivatives as inhibitors of TAFIa | SANOFI (FR) | 2013-03-05 | — | — | US | disclosed |
| US-20100035930-A1 | UREA AND SULFAMIDE DERIVATIVES AS INHIBITORS OF TAFIa | SANOFI-AVENTIS (FR) | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035930-A1 | UREA AND SULFAMIDE DERIVATIVES AS INHIBITORS OF TAFIa | TFPI, TFPI2, SERPINE1 | CTSD 147/4885ANPEP 455/4885OPRK1 4194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.