SCHEMBL320296

SCHEMBL320296

C=Cc1c(Br)cccc1Br

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
ALDH1A1 P00352 6/20 0.35
TSHR P16473 2/20 0.35
MAOB P27338 2/20 0.34
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
CA5A P35218 1/20 0.31
CA9 Q16790 1/20 0.31
PDPK1 O15530 1/20 0.31
PLCG1 P19174 1/20 0.31
AHR P35869 1/20 0.31
MAPK1 P28482 2/20 0.31
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
KDM4E B2RXH2 1/20 0.30
HDAC8 Q9BY41 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29947357 0.88 MAOB (0.42) TP53TDP1MAOBKDM4E
SCHEMBL1986111 0.88 MAOB (0.42) TP53TDP1MAOBKDM4E
SCHEMBL8010113 0.85 ALDH1A1 (0.39) TP53TDP1ALDH1A1MAOB
SCHEMBL27880022 0.83 MAOB (0.33) TP53TDP1ALDH1A1MAOBCA1
SCHEMBL22898375 0.83 BACE1 (0.36) TP53TDP1ALDH1A1TSHRMAOB
SCHEMBL23043311 0.83 ALDH1A1 (0.44) TP53TDP1ALDH1A1TSHRPDPK1
SCHEMBL31256460 0.83 ALDH1A1 (0.44) TP53TDP1ALDH1A1TSHRPDPK1
SCHEMBL16293471 0.83 ALDH1A1 (0.48) TP53TDP1ALDH1A1TSHRMAOB
SCHEMBL6560397 0.83 MAOB (0.44) TP53TDP1ALDH1A1MAOBCA1
SCHEMBL16950810 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 418 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10946697-B2 Tire provided with a tread comprising a diene elastomer, a thermoplastic elastomer and a thermoplastic resin having polyphenylene ether patterns COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2021-03-16 US claimed
US-10780740-B2 Tire provided with a tread comprising a diene elastomer and thermoplastic elastomer system COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2020-09-22 US claimed
EP-3099742-B1 TYRE PROVIDED WITH A TREAD COMPRISING A THERMOPLASTIC ELASTOMER MICHELIN & CIE (FR) 2020-04-15 EP claimed
US-10369842-B2 Tire provided with a tread comprising a thermoplastic elastomer COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2019-08-06 US claimed
EP-3390073-A1 TYRE PROVIDED WITH A TREAD COMPRISING A DIENE ELASTOMER, A THERMOPLASTIC ELASTOMER AND A PEROXIDE Compagnie Générale des Etablissements Michelin (FR) 2018-10-24 EP claimed
US-20180186184-A1 TIRE PROVIDED WITH A TREAD COMPRISING A DIENE ELASTOMER, A THERMOPLASTIC ELASTOMER AND A THERMOPLASTIC RESIN HAVING POLYPHENYLENE ETHER PATTERNS COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2018-07-05 US claimed
US-20180178584-A1 TIRE PROVIDED WITH A TREAD COMPRISING A DIENE ELASTOMER AND THERMOPLASTIC ELASTOMER SYSTEM COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2018-06-28 US claimed
EP-3310584-A1 TYRE PROVIDED WITH A TREAD COMPRISING A DIENE ELASTOMER, A THERMOPLASTIC ELASTOMER AND A THERMOPLASTIC RESIN HAVING POLYPHENYLENE ETHER PATTERNS Compagnie Générale des Etablissements Michelin (FR) 2018-04-25 EP claimed
EP-3310585-A1 TYRE PROVIDED WITH A TREAD COMPRISING A DIENE ELASTOMER AND THERMOPLASTIC ELASTOMER SYSTEM Compagnie Générale des Etablissements Michelin (FR) 2018-04-25 EP claimed
US-20170313130-A1 TIRE PROVIDED WITH A TREAD COMPRISING A THERMOPLASTIC ELASTOMER AND A DIENE ELASTOMER COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2017-11-02 US claimed
US-20160347121-A1 MULTILAYER LAMINATE FOR A TIRE COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2016-12-01 US claimed
US-20160339743-A1 TIRE PROVIDED WITH A TREAD COMPRISING A THERMOPLASTIC ELASTOMER COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2016-11-24 US claimed
US-9448219-B2 Electro-mechanical switches and methods of use thereof MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2016-09-20 US claimed
WO-2016001094-A1 TYRE PROVIDED WITH A TREAD COMPRISING A THERMOPLASTIC ELASTOMER AND A DIENE ELASTOMER COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2016-01-07 WO claimed
WO-2015113966-A1 TYRE PROVIDED WITH A TREAD COMPRISING A THERMOPLASTIC ELASTOMER COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2015-08-06 WO claimed
US-8441081-B2 Electro-mechanical switches and methods of use thereof MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2013-05-14 US claimed
WO-2010011733-A2 ELECTRO-MECHANICAL SWITCHES AND METHODS OF USE THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2010-01-28 WO claimed
WO-2007145657-A2 INITIATED CHEMICAL VAPOR DEPOSITION OF VINYL POLYMERS FOR THE ENCAPSULATION OF PARTICLES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2007-12-21 WO claimed
US-4698393-A FRIEDEL CRAFTS CATALYSTS AND SUSPENSION POLYMERIZATION; MATERIALS HANDLING RAYCHEM CORPORATION (US) 1987-10-06 US claimed
US-4168365-A Flame-retardant phenolic resin MATSUSHITA ELECTRIC WORKS, LTD. (JP) 1979-09-18 US claimed