SCHEMBL6560397

SCHEMBL6560397

C=Cc1c(O)cccc1Br

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.44
PTK6 Q13882 1/20 0.40
TTR P02766 1/20 0.36
CA2 P00918 6/20 0.36
CA1 P00915 5/20 0.36
TDP1 Q9NUW8 3/20 0.36
ALDH1A1 P00352 2/20 0.36
EGFR P00533 2/20 0.36
LMNA P02545 2/20 0.36
FYN P06241 2/20 0.36
MMP9 P14780 2/20 0.36
HPGD P15428 2/20 0.36
ALOX15 P16050 2/20 0.36
RECQL P46063 2/20 0.36
HSD17B10 Q99714 2/20 0.36
CDK2 P24941 2/20 0.36
CA6 P23280 2/20 0.36
ADAMTS4 O75173 1/20 0.36
MMP2 P08253 1/20 0.36
MMP8 P22894 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4551394 0.85 ALDH1A1 (0.47) TTRCA2CA1TDP1ALDH1A1
SCHEMBL320296 0.83 TP53 (0.37) MAOBCA2CA1TDP1ALDH1A1
SCHEMBL674874 0.77 MAOB (0.49) MAOBPTK6TTRCA2CA1
SCHEMBL16632534 0.76 MAOB (0.43) MAOBPTK6TTRCA2CA1
Phenol SCHEMBL27491460 0.74 CA2 (0.52) TTRCA2CA1TDP1ALDH1A1
SCHEMBL2098518 0.74 ERN1 (0.41) TTRCA2CA1TDP1ALDH1A1
SCHEMBL7197107 0.74 TDP1 (0.38) TTRCA2CA1TDP1ALDH1A1
SCHEMBL9567898 0.74 CA2 (0.38) TTRCA2CA1TDP1ALDH1A1
SCHEMBL8010113 0.74 ALDH1A1 (0.39) MAOBTDP1ALDH1A1MEN1KMT2A
SCHEMBL28763215 0.74 MAOB (0.42) MAOBPTK6TTRCA2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0983126-B1 FAST-SETTING LATEX COATINGS AND FORMULATIONS DOW GLOBAL TECHNOLOGIES INC (US) 2003-06-25 EP claimed
EP-0882079-B1 REVERSIBLE AND IRREVERSIBLE WATER-BASED COATINGS DOW CHEMICAL CO (US) 2003-01-08 EP claimed
JP-2002502449-A 2002-01-22 JP claimed
EP-0983126-A1 FAST-SETTING LATEX COATINGS AND FORMULATIONS THE DOW CHEMICAL COMPANY (US) 2000-03-08 EP claimed
EP-0882079-A1 REVERSIBLE AND IRREVERSIBLE WATER-BASED COATINGS THE DOW CHEMICAL COMPANY (US) 1998-12-09 EP claimed
WO-1998052698-A1 FAST-SETTING LATEX COATINGS AND FORMULATIONS THE DOW CHEMICAL COMPANY (US) 1998-11-26 WO claimed
US-5674934-A POLYMER HAVING STRONG, BICARBONATE-ASSOCIATED CATIONIC AND WEAK ANIONIC PENDANT GROUPS THE DOW CHEMICAL COMPANY (US) 1997-10-07 US claimed
WO-1997031042-A1 REVERSIBLE AND IRREVERSIBLE WATER-BASED COATINGS THE DOW CHEMICAL COMPANY (US) 1997-08-28 WO claimed
US-5021296-A Increased adhesiveness; electroless deposition of metallic interfaces HITACHI, LTD. (JP) 1991-06-04 US claimed
CN-112888498-B Composition useful for making acid gas separation membranes 住友化学株式会社 2023-07-14 CN disclosed
US-11485708-B2 Compounds for treatment of PD-L1 diseases CHEMOCENTRYX, INC. (US) 2022-11-01 US disclosed
EP-3986392-A2 COMPOUNDS FOR TREATMENT OF PD-L1 DISEASES ChemoCentryx, Inc. (US) 2022-04-27 EP disclosed
CN-110035992-B Process for preparing 3-substituted 2-vinylphenyl sulfonates 拜耳作物科学股份公司 2022-04-05 CN disclosed
CN-109641822-B Process for preparing substituted styrene derivatives 拜耳作物科学股份公司 2022-03-11 CN disclosed
US-5910532-A COMPOSITION COMPRISING POLYMER CONTAINING STRONG CATIONIC GROUPS AND ACID GROUPS DISPERSED IN MULTISOLVENT MEDIUM CONTAINING WATER, LOW BOILING POLAR ORGANIC SOLVENT, HIGH BOILING SOLVENT THE DOW CHEMICAL COMPANY (US) 1999-06-08 US disclosed
EP-0882079-A1 REVERSIBLE AND IRREVERSIBLE WATER-BASED COATINGS THE DOW CHEMICAL COMPANY (US) 1998-12-09 EP disclosed
WO-1998053796-A1 MULTISOLVENT-BASED FILM-FORMING COMPOSITIONS THE DOW CHEMICAL COMPANY (US) 1998-12-03 WO disclosed
US-5674934-A POLYMER HAVING STRONG, BICARBONATE-ASSOCIATED CATIONIC AND WEAK ANIONIC PENDANT GROUPS THE DOW CHEMICAL COMPANY (US) 1997-10-07 US disclosed
WO-1997031042-A1 REVERSIBLE AND IRREVERSIBLE WATER-BASED COATINGS THE DOW CHEMICAL COMPANY (US) 1997-08-28 WO disclosed
US-5021296-A Increased adhesiveness; electroless deposition of metallic interfaces HITACHI, LTD. (JP) 1991-06-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11485708-B2 Compounds for treatment of PD-L1 diseases CD274, PDCD1, PDCD1LG2 MAOB 1155/4885PTK6 3759/4885TTR 1497/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.