SCHEMBL3203111

SCHEMBL3203111

CN(C)c1ccc(C2c3ccccc3-c3ccccc32)c(C(=N)c2ccccc2)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.39
TSHR P16473 2/20 0.39
CYP3A4 P08684 1/20 0.39
ALOX15 P16050 1/20 0.39
HBB P68871 1/20 0.39
RAB9A P51151 3/20 0.36
KMT2A Q03164 3/20 0.36
HPGD P15428 2/20 0.36
NPC1 O15118 2/20 0.36
MEN1 O00255 2/20 0.36
KCNK3 O14649 1/20 0.35
ALDH1A1 P00352 3/20 0.35
GFER P55789 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
MAPT P10636 1/20 0.34
F10 P00742 3/20 0.34
F7 P08709 1/20 0.34
F3 P13726 1/20 0.34
GPR3 P46089 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3200758 0.81 F10 (0.30) F10
SCHEMBL3212980 0.81 F7 (0.35) MAPK1TSHRCYP3A4ALOX15HBB
SCHEMBL3207517 0.81 PDK2 (0.35) TSHRRAB9AKMT2AHPGDNPC1
SCHEMBL3193749 0.79 MAPK1 (0.33) MAPK1TSHRCYP3A4ALOX15HBB
SCHEMBL3209968 0.79 CYP1A2 (0.39) ALOX15HBBKMT2AMAPTF10
SCHEMBL3199308 0.78 MAPK1 (0.36) MAPK1TSHRCYP3A4ALOX15HBB
SCHEMBL3202608 0.77 SLC10A2 (0.36) F10GPR3PDK2
SCHEMBL3213680 0.77 KDM4E (0.36) TSHRRAB9AHPGDNPC1ALDH1A1
SCHEMBL3191412 0.76 CYP2D6 (0.35) MAPK1TSHRCYP3A4RAB9AKMT2A
SCHEMBL3681430 0.72 RAB9A (0.36) MAPK1TSHRCYP3A4ALOX15HBB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7671226-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-02 US disclosed
EP-1426379-B1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME SUMITOMO CHEMICAL CO (JP) 2009-11-11 EP disclosed
US-7439379-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL CO., LTD. (JP) 2008-10-21 US disclosed