SCHEMBL3203144

SCHEMBL3203144

CC1=CC(C)=C(c2ccc3ccccc3c2C(=O)c2ccccc2)C1C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 1/20 0.40
HTT P42858 2/20 0.38
MAPT P10636 5/20 0.36
GAA P10253 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
ALDH1A1 P00352 5/20 0.35
HPGD P15428 4/20 0.35
CNR2 P34972 1/20 0.35
TAS1R3 Q7RTX0 1/20 0.35
TAS1R1 Q7RTX1 1/20 0.35
TAS1R2 Q8TE23 1/20 0.35
KDM4E B2RXH2 4/20 0.35
LMNA P02545 2/20 0.34
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
CYP1A2 P05177 1/20 0.33
GLA P06280 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3199652 0.87 HPGD (0.40) L3MBTL1HTTMAPTALDH1A1HPGD
SCHEMBL3192452 0.84 TAS1R3 (0.34) L3MBTL1MAPTGAAALDH1A1HPGD
SCHEMBL3203080 0.81 NPC1 (0.41) L3MBTL1NPC1RAB9AHTTMAPT
SCHEMBL3191780 0.75 ERN1 (0.43) L3MBTL1NPC1RAB9AHTTMAPT
SCHEMBL3198360 0.74 ALDH1A1 (0.46) HTTMAPTNPSR1ALDH1A1HPGD
SCHEMBL3207922 0.74 NPC1 (0.42) L3MBTL1NPC1RAB9AHTTMAPT
SCHEMBL3201586 0.73 NPC1 (0.44) L3MBTL1NPC1RAB9AHTTMAPT
SCHEMBL28928988 0.73 MEN1 (0.46) L3MBTL1NPC1RAB9AHTTMAPT
SCHEMBL3209767 0.72 ALDH1A1 (0.50) L3MBTL1NPC1RAB9AHTTMAPT
SCHEMBL3192534 0.72 TDP1 (0.44) L3MBTL1NPC1RAB9AHTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7732643-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-08 US disclosed
US-7671226-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-02 US disclosed
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME HANAOKA HIDENORI 2010-02-25 US disclosed
EP-1426379-B1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME SUMITOMO CHEMICAL CO (JP) 2009-11-11 EP disclosed
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same HANAOKA HIDENORI 2009-02-26 US disclosed
US-7439379-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL CO., LTD. (JP) 2008-10-21 US disclosed
US-20040242410-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-02 US disclosed
EP-1426379-A1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME Sumitomo Chemical Company, Limited (JP) 2004-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same C1R, C1S, AP1M1 L3MBTL1 1838/4885NPC1 2173/4885RAB9A 1759/4885
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME C1R, C1S, AP1M1 L3MBTL1 1838/4885NPC1 2173/4885RAB9A 1759/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.