Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2882759 | 0.85 | USP2 (0.33) | USP2ALDH1A1SPHK1MGAM | |
| SCHEMBL8032603 | 0.83 | USP2 (0.34) | USP2SPHK1MGAM | |
| SCHEMBL10380957 | 0.82 | MEN1 (0.44) | USP2ALDH1A1TSHRHTT | |
| SCHEMBL7554513 | 0.82 | MEN1 (0.44) | USP2ALDH1A1TSHRHTT | |
| SCHEMBL2947569 | 0.82 | MEN1 (0.44) | USP2ALDH1A1TSHRHTT | |
| SCHEMBL6899279 | 0.82 | MGAM (0.41) | USP2ALDH1A1SPHK1MGAMTSHR | |
| SCHEMBL5189905 | 0.81 | USP2 (0.44) | USP2ALDH1A1SPHK1MGAMTSHR | |
| SCHEMBL9227814 | 0.81 | USP2 (0.44) | USP2SPHK1MGAMHSD17B10TDP1 | |
| SCHEMBL28724981 | 0.80 | ALDH1A1 (0.41) | ALDH1A1HSD17B10TDP1TSHR | |
| SCHEMBL10990567 | 0.79 | USP2 (0.55) | USP2ALDH1A1SPHK1MGAMTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3494960-B1 | STABILIZED COMPOSITIONS OF ALKYLATING AGENTS AND METHODS OF USING SAME | HELSINN HEALTHCARE SA (CH) | 2020-11-25 | — | — | EP | disclosed |
| EP-3494960-A1 | STABILIZED COMPOSITIONS OF ALKYLATING AGENTS AND METHODS OF USING SAME | Helsinn Healthcare SA (CH) | 2019-06-12 | — | — | EP | disclosed |
| US-20140142193-A1 | Stabilized Compositions Of Alkylating Agents And Methods Of Using Same | ACTELION PHARMACEUTICALS, LTD. (CH) | 2014-05-22 | — | — | US | disclosed |
| US-8501817-B2 | Stabilized compositions of alkylating agents and methods of using same | CEPTARIS THERAPEUTICS, INC. (US) | 2013-08-06 | — | — | US | disclosed |
| US-20100029783-A9 | STABILIZED COMPOSITIONS OF ALKYLATING AGENTS AND METHODS OF USING SAME | HELSINN HEALTHCARE SA (CH) | 2010-02-04 | — | — | US | disclosed |
| US-20090247645-A1 | STABILIZED COMPOSITIONS OF ALKYLATING AGENTS AND METHODS OF USING SAME | HELSINN BIREX PHARMACEUTICALS LIMITED (IE) | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247645-A1 | STABILIZED COMPOSITIONS OF ALKYLATING AGENTS AND METHODS OF USING SAME | MGMT, ETV6, POLH | USP2 2427/4885ALDH1A1 4081/4885SPHK1 549/4885 |
| US-20140142193-A1 | Stabilized Compositions Of Alkylating Agents And Methods Of Using Same | MGMT, ETV6, POLH | USP2 2427/4885ALDH1A1 4081/4885SPHK1 549/4885 |
| US-20100029783-A9 | STABILIZED COMPOSITIONS OF ALKYLATING AGENTS AND METHODS OF USING SAME | MGMT, ETV6, POLH | USP2 2427/4885ALDH1A1 4081/4885SPHK1 549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.