Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.95 |
| ▸ | MAOB | P27338 | 6/20 | 0.95 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.95 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chromone SCHEMBL29369932 | 0.98 | MAOA (1.00) | MAOAMAOBFTOACHEGRM5 | |
| Chromone SCHEMBL30075941 | 0.98 | MAOA (1.00) | MAOAMAOBFTOACHEGRM5 | |
| Chromone SCHEMBL37994 | 0.98 | MAOA (1.00) | MAOAMAOBFTOACHEGRM5 | |
| Chromone SCHEMBL6347379 | 0.98 | MAOA (1.00) | MAOAMAOBFTOACHEGRM5 | |
| Chromone SCHEMBL28268880 | 0.98 | MAOA (1.00) | MAOAMAOBFTOACHEGRM5 | |
| Chromone SCHEMBL31277121 | 0.95 | MAOA (0.95) | MAOAMAOBFTOACHEGRM5 | |
| Chromone SCHEMBL1034108 | 0.95 | MAOA (0.95) | MAOAMAOBFTOACHEGRM5 | |
| Chromone SCHEMBL29628171 | 0.95 | MAOA (0.95) | MAOAMAOBFTOACHEGRM5 | |
| Chromone SCHEMBL31622445 | 0.95 | MAOA (0.95) | MAOAMAOBFTOACHEGRM5 | |
| Chromone SCHEMBL29374821 | 0.95 | MAOA (0.95) | MAOAMAOBFTOACHEGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022124989-A1 | THERMOPHOTOCHROMIC POLYMER AND METHOD OF PREPARING THERMOPHOTOCHROMIC POLYMER | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2022-06-16 | — | — | WO | disclosed |
| CN-109180625-A | A kind of preparation method of seleno flavone compound | 温州医科大学 | 2019-01-11 | — | — | CN | disclosed |
| US-7666646-B2 | Crystal structure of human Pim-1 kinase protein complexes and binding pockets thereof, and uses thereof in drug design | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2010-02-23 | — | — | US | disclosed |
| US-20070031956-A1 | Crystal structure of human PIM-1 kinase protein complexes and binding pockets thereof, and uses thereof in drug design | VERTEX PHARMACEUTICALS INCORPORATED | 2007-02-08 | — | — | US | disclosed |
| WO-2004090106-A2 | CRYSTAL STRUCTURES OF HUMAN PIM-1 KINASE PROTEIN COMPLEXES AND BINDING POCKETS THEREOF, AND USES THEREOF IN DRUG DESIGN | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2004-10-21 | — | — | WO | disclosed |