SCHEMBL3203854

SCHEMBL3203854

CC(C)c1cccc(C(C)C)c1N/N=C/c1ccccc1C1c2ccccc2-c2ccccc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPFFR1 Q9GZQ6 1/20 0.34
NPFFR2 Q9Y5X5 1/20 0.34
LMNA P02545 8/20 0.32
KMT2A Q03164 6/20 0.32
MAPT P10636 6/20 0.32
SMN1; SMN2 Q16637 4/20 0.32
NPC1 O15118 4/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 5/20 0.32
ALDH1A1 P00352 3/20 0.32
GAA P10253 3/20 0.32
RAB9A P51151 2/20 0.32
HPGD P15428 2/20 0.32
HTT P42858 2/20 0.31
MDM2 Q00987 1/20 0.31
POLB P06746 1/20 0.31
ATM Q13315 1/20 0.31
GFER P55789 1/20 0.31
F2 P00734 1/20 0.30
DPP4 P27487 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3203860 1.00 NPFFR1 (0.34) NPFFR1NPFFR2LMNAKMT2AMAPT
SCHEMBL3199364 0.82 MAPT (0.31) LMNAKMT2AMAPTSMN1; SMN2NPC1
SCHEMBL3199371 0.82 MAPT (0.31) LMNAKMT2AMAPTSMN1; SMN2NPC1
SCHEMBL3208763 0.79
SCHEMBL3208758 0.79
SCHEMBL3209769 0.78 SIGMAR1 (0.31)
SCHEMBL3209771 0.78 SIGMAR1 (0.31)
SCHEMBL3199085 0.77 MAPT (0.37) LMNAKMT2AMAPTSMN1; SMN2NPC1
SCHEMBL3205380 0.76 MAPT (0.54) LMNAKMT2AMAPTSMN1; SMN2NPC1
SCHEMBL3205379 0.76 MAPT (0.54) LMNAKMT2AMAPTSMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7671226-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-02 US disclosed
EP-1426379-B1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME SUMITOMO CHEMICAL CO (JP) 2009-11-11 EP disclosed
US-7439379-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL CO., LTD. (JP) 2008-10-21 US disclosed