Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | JUN | P05412 | 4/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.39 |
| ▸ | RELA | Q04206 | 4/20 | 0.39 |
| ▸ | FOS | P01100 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.37 |
| ▸ | TUBB | P07437 | 1/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1373222 | 0.88 | SYK (0.43) | SYKKDM4EJUNNFKB1NFKB2 | |
| SCHEMBL15636201 | 0.82 | SYK (0.45) | SYKKDM4EJUNNFKB1NFKB2 | |
| SCHEMBL15636051 | 0.80 | SYK (0.43) | SMN1; SMN2SYKKDM4EJUNNFKB1 | |
| SCHEMBL15635108 | 0.80 | KDM4E (0.46) | SYKKDM4EJUNNFKB1NFKB2 | |
| SCHEMBL6217104 | 0.79 | HPGD (0.46) | GAASMN1; SMN2SYKKDM4EJUN | |
| SCHEMBL15635500 | 0.78 | SYK (0.42) | GAASYKKDM4EJUNNFKB1 | |
| SCHEMBL31697314 | 0.77 | KDM4E (0.50) | GAAKDM4ETSHRNPSR1ALDH1A1 | |
| SCHEMBL1498542 | 0.77 | KDM4E (0.50) | GAAKDM4ETSHRNPSR1ALDH1A1 | |
| SCHEMBL2085018 | 0.77 | SYK (0.41) | SYKKDM4EJUNNFKB1NFKB2 | |
| SCHEMBL24834467 | 0.76 | KDM4E (0.48) | SYKKDM4EMAPTTSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100035756-A1 | TRIAZOLOPHYRIDINE DERIVATIVES AS HERBICIDES | SYNGENTA LIMITED (GB) | 2010-02-11 | — | — | US | disclosed |
| EP-2046788-A1 | TRIAZOLOPYRIDINE DERIVATIVES AS HERBICIDES | Syngeta Participations AG (CH) | 2009-04-15 | — | — | EP | disclosed |
| WO-2008006540-A1 | TRIAZOLOPYRIDINE DERIVATIVES AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2008-01-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035756-A1 | TRIAZOLOPHYRIDINE DERIVATIVES AS HERBICIDES | DDT, CYP1A1, NAT1 | GAA 553/4885SMN1; SMN2 4350/4885SYK 2478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.