Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 1/20 | 0.83 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.83 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.83 |
| ▸ | GABRR1 | P24046 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.50 |
| ▸ | GABRP | O00591 | 1/20 | 0.50 |
| ▸ | GABRD | O14764 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL28658007 | 1.00 | GLRA1 (0.83) | GLRA1SLC6A9OR51E2GABRR1LMNA | |
| Glycine SCHEMBL9640004 | 1.00 | GLRA1 (0.83) | GLRA1SLC6A9OR51E2GABRR1LMNA | |
| Glycine SCHEMBL6386791 | 1.00 | — | — | |
| Glycine SCHEMBL93765 | 0.91 | GLRA1 (1.00) | GLRA1SLC6A9OR51E2GABRR1LMNA | |
| Glycine SCHEMBL391786 | 0.91 | GLRA1 (1.00) | GLRA1SLC6A9OR51E2GABRR1LMNA | |
| Glycine SCHEMBL2116443 | 0.91 | — | — | |
| Glycine SCHEMBL6675874 | 0.91 | GLRA1 (1.00) | GLRA1SLC6A9OR51E2GABRR1LMNA | |
| Glycine SCHEMBL3640989 | 0.91 | GLRA1 (1.00) | GLRA1SLC6A9OR51E2GABRR1LMNA | |
| Glycine SCHEMBL13169653 | 0.91 | — | — | |
| Glycine SCHEMBL391027 | 0.91 | GLRA1 (1.00) | GLRA1SLC6A9OR51E2GABRR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152845-B1 | HARD SURFACE CLEANING COMPOSITION WITH HYDROPHILIZING AGENT AND METHOD FOR CLEANING HARD SURFACES | SOLVAY USA INC (US) | 2017-03-29 | — | — | EP | claimed |
| US-9220725-B2 | Cationic latex as a carrier for bioactive ingredients and methods for making and using the same | MALLARD CREEK POLYMERS, INC. (US) | 2015-12-29 | — | — | US | claimed |
| CN-101541312-B | Anionic latex as a carrier for bioactive ingredients | MALLARD CREEK POLYMERS INC | 2013-05-22 | — | — | CN | claimed |
| EP-2094243-B1 | ANIONIC LATEX AS A CARRIER FOR BIOACTIVE INGREDIENTS AND METHODS FOR MAKING AND USING THE SAME | MALLARD CREEK POLYMERS INC (US) | 2013-04-17 | — | — | EP | claimed |
| EP-2061481-B1 | CATIONIC LATEX AS A CARRIER FOR BIOACTIVE INGREDIENTS AND METHODS FOR MAKING AND USING THE SAME | MALLARD CREEK POLYMERS INC (US) | 2012-12-12 | — | — | EP | claimed |
| US-7781498-B2 | Cationic latex as a carrier for bioactive ingredients and methods for making and using the same | MALLARD CREEK POLYMERS, INC. (US) | 2010-08-24 | — | — | US | claimed |
| CN-101743123-A | Cationic latex as a carrier for bioactive ingredients and methods of making and using the same | MALLARD CREEK POLYMERS INC | 2010-06-16 | — | — | CN | claimed |
| EP-2134324-A2 | CATIONIC LATEX AS A CARRIER FOR BIOACTIVE INGREDIENTS AND METHODS FOR MAKING AND USING THE SAME | Mallard Creek Polymers, Inc (US) | 2009-12-23 | — | — | EP | claimed |
| CN-101541312-A | Anionic latex as a carrier for bioactive ingredients | MALLARD CREEK POLYMERS INC (US) | 2009-09-23 | — | — | CN | claimed |
| EP-2094243-A2 | ANIONIC LATEX AS A CARRIER FOR BIOACTIVE INGREDIENTS AND METHODS FOR MAKING AND USING THE SAME | Mallard Creek Polymers, Inc (US) | 2009-09-02 | — | — | EP | claimed |
| WO-2008156509-A2 | CATIONIC LATEX AS A CARRIER FOR BIOACTIVE INGREDIENTS AND METHODS FOR MAKING AND USING THE SAME | MALLARD CREEK POLYMERS, INC. (US) | 2008-12-24 | — | — | WO | claimed |
| WO-2008088394-A2 | ANIONIC LATEX AS A CARRIER FOR BIOACTIVE INGREDIENTS | MALLARD CREEK POLYMERS (US) | 2008-07-24 | — | — | WO | claimed |
| US-20080057049-A1 | Cationic latex as a carrier for bioactive ingredients and methods for making and using the same | MALLARD CREEK POLYMERS, INC. | 2008-03-06 | — | — | US | claimed |
| WO-2008024509-A2 | CATIONIC LATEX AS A CARRIER FOR BIOACTIVE INGREDIENTS AND METHODS FOR MAKING AND USING THE SAME | MALLARD CREEK POLYMERS, INC. (US) | 2008-02-28 | — | — | WO | claimed |
| US-20070149694-A1 | Cationic latex as a carrier for bioactive ingredients and methods for making and using the same | MALLARD CREEK POLYMERS, INC. | 2007-06-28 | — | — | US | claimed |
| EP-1196523-B1 | CLEANSING COMPOSITION COMPRISING A WATER SOLUBLE OR WATER DISPERSIBLE POLYMER | RHODIA CHIMIE SA (FR) | 2004-09-15 | — | — | EP | claimed |
| EP-1196523-A1 | CLEANSING COMPOSITION COMPRISING A WATER SOLUBLE OR WATER DISPERSIBLE POLYMER | Rhodia Chimie (FR) | 2002-04-17 | — | — | EP | claimed |
| WO-2001005920-A1 | CLEANSING COMPOSITION COMPRISING A WATER SOLUBLE OR WATER DISPERSIBLE POLYMER | RHODIA CHIMIE (FR) | 2001-01-25 | — | — | WO | claimed |
| EP-1022941-A1 | SYSTEM BASED ON A BIOCIDE AND A POLYETHER SILICON FOR DISINFECTING HARD SURFACES | RHODIA CHIMIE (FR) | 2000-08-02 | — | — | EP | claimed |
| WO-1999018784-A1 | SYSTEM BASED ON A BIOCIDE AND A POLYETHER SILICON FOR DISINFECTING HARD SURFACES | RHODIA CHIMIE (FR) | 1999-04-22 | — | — | WO | claimed |