SCHEMBL3204634

SCHEMBL3204634

CC1=CC(C)C(c2ccc3ccccc3c2C(=N)C2CCCCC2)=C1C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 1/20 0.37
TAS1R1 Q7RTX1 1/20 0.37
TAS1R2 Q8TE23 1/20 0.37
ALDH1A1 P00352 6/20 0.35
KDM4E B2RXH2 5/20 0.35
LMNA P02545 3/20 0.35
RAB9A P51151 2/20 0.35
POLB P06746 2/20 0.35
HPGD P15428 2/20 0.35
GAA P10253 1/20 0.35
CYP2C19 P33261 2/20 0.33
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
HTT P42858 1/20 0.32
CNR1 P21554 3/20 0.32
KCNJ11 Q14654 1/20 0.32
ACP3 P15309 1/20 0.31
SALL4 Q9UJQ4 1/20 0.31
EPHX1 P07099 2/20 0.31
HSD17B10 Q99714 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3216950 0.82 TAS1R3 (0.38) TAS1R3TAS1R1TAS1R2ALDH1A1KDM4E
SCHEMBL3207418 0.80 NPC1 (0.34) KDM4ERAB9AMAPT
SCHEMBL3202746 0.79 NPC1 (0.33) ALDH1A1LMNARAB9APOLBGAA
SCHEMBL3206813 0.79 ALDH1A1 (0.36) TAS1R3TAS1R1TAS1R2ALDH1A1KDM4E
SCHEMBL3203942 0.78 TAS1R3 (0.30) TAS1R3TAS1R1TAS1R2RAB9A
SCHEMBL3214107 0.78 ALDH1A1 (0.36) TAS1R3TAS1R1TAS1R2ALDH1A1KDM4E
SCHEMBL3200838 0.74 NPSR1 (0.31) ALDH1A1KDM4ELMNAPOLBHPGD
SCHEMBL3192314 0.74 CYP1A2 (0.37) TAS1R3TAS1R1TAS1R2CYP2C19CYP1A2
SCHEMBL3204538 0.73 ALDH1A1 (0.36) TAS1R3TAS1R1TAS1R2ALDH1A1KDM4E
SCHEMBL3208767 0.73 ALDH1A1 (0.36) TAS1R3TAS1R1TAS1R2ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7732643-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-08 US disclosed
US-7671226-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-02 US disclosed
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME HANAOKA HIDENORI 2010-02-25 US disclosed
EP-1426379-B1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME SUMITOMO CHEMICAL CO (JP) 2009-11-11 EP disclosed
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same HANAOKA HIDENORI 2009-02-26 US disclosed
US-7439379-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL CO., LTD. (JP) 2008-10-21 US disclosed
US-20040242410-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-02 US disclosed
EP-1426379-A1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME Sumitomo Chemical Company, Limited (JP) 2004-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same C1R, C1S, AP1M1 TAS1R3 2410/4885TAS1R1 1939/4885TAS1R2 3007/4885
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME C1R, C1S, AP1M1 TAS1R3 2410/4885TAS1R1 1939/4885TAS1R2 3007/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.