Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | PPARG | P37231 | 10/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | LIPE | Q05469 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3215665 | 0.91 | PPARG (0.61) | LMNAPPARGSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL7935274 | 0.87 | LMNA (0.55) | LMNASMN1; SMN2ALDH1A1HPGDCYP1A2 | |
| SCHEMBL3213597 | 0.86 | PPARG (0.59) | LMNAPPARGSMN1; SMN2LIPE | |
| SCHEMBL3213617 | 0.86 | PPARG (0.59) | LMNAPPARGSMN1; SMN2LIPE | |
| SCHEMBL3209482 | 0.85 | LMNA (0.50) | LMNAPPARGSMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL3218932 | 0.85 | PPARG (0.51) | LMNAPPARGSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL3206746 | 0.85 | PPARG (0.60) | LMNAPPARGSMN1; SMN2LIPE | |
| SCHEMBL3219172 | 0.85 | PPARG (0.60) | LMNAPPARGSMN1; SMN2LIPE | |
| SCHEMBL3198707 | 0.85 | PPARG (0.60) | LMNAPPARGSMN1; SMN2LIPE | |
| SCHEMBL5111569 | 0.83 | MAPK1 (0.47) | LMNASMN1; SMN2ALDH1A1HPGDLIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100041892-A1 | Therapeutic agent for diabetes | ABE HIDENORI | 2010-02-18 | — | — | US | disclosed |
| US-20090270631-A1 | Therapeutic agent for diabetes | ABE HIDENORI | 2009-10-29 | — | — | US | disclosed |
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| US-20080009530-A1 | Therapeutic Agent for Diabetes | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-01-10 | — | — | US | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270631-A1 | Therapeutic agent for diabetes | FABP4, SLC5A1, SLC5A2 | LMNA 1909/4885PPARG 31/4885SMN1; SMN2 3845/4885 |
| US-20080009530-A1 | Therapeutic Agent for Diabetes | FABP4, SLC5A1, SLC5A2 | LMNA 2486/4885PPARG 30/4885SMN1; SMN2 4093/4885 |
| US-20100041892-A1 | Therapeutic agent for diabetes | FABP4, SLC5A1, SLC5A2 | LMNA 1909/4885PPARG 31/4885SMN1; SMN2 3845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.