SCHEMBL320488

SCHEMBL320488

C[Si](C)(C)CC(N)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11142184 0.83
SCHEMBL11259022 0.81
SCHEMBL5146321 0.78
SCHEMBL5487841 0.75 MEN1 (0.30)
SCHEMBL3258299 0.75 CRBN (0.42)
SCHEMBL537434 0.72 SOAT1 (0.36)
SCHEMBL5088974 0.71 TDP1 (0.41)
SCHEMBL8316128 0.71 PKM (0.31)
SCHEMBL6270070 0.71 HTT (0.31)
SCHEMBL8954744 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3454 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118290506-A Method for carrying out rApp modification on oligonucleotide based on solid phase synthesis 杭州联川生物技术股份有限公司 2024-07-05 CN claimed
CN-118271378-A Sugar ring modified nucleoside phosphoramidite monomer and preparation method and application thereof 中国科学院深圳先进技术研究院 2024-07-02 CN claimed
CN-118255826-A Preparation method of 4' -azidopyrimidine nucleoside and analogue thereof 中国海洋大学 2024-06-28 CN claimed
CN-118201925-A Macrocyclic compounds and methods of making the same 詹森生物科技公司 2024-06-14 CN claimed
CN-113710684-B Process for producing peptide compound 日产化学株式会社 2024-06-11 CN claimed
CN-117920348-B Cation exchange resin supported catalyst, preparation method thereof and preparation method of cEt-U phosphoramidite monomer intermediate 凯莱英生命科学技术(天津)有限公司 2024-06-07 CN claimed
CN-118054072-A Electrolyte for lithium battery and lithium battery 成都职业技术学院 2024-05-17 CN claimed
CN-117964667-A Chemical synthesis method of 5' -adenosine pyrophosphorylation modified oligonucleotide 苏州金唯智生物科技有限公司 2024-05-03 CN claimed
CN-117949549-A Method for measuring sorbitol nucleating agent content in polypropylene 中国石油化工股份有限公司 2024-04-30 CN claimed
CN-117920348-A Cation exchange resin supported catalyst, preparation method thereof and preparation method of cEt-U phosphoramidite monomer intermediate 凯莱英生命科学技术(天津)有限公司 2024-04-26 CN claimed
CN-85106673-A Curable polymeric composition 1987-03-25 CN claimed
US-4602092-A Method for making phosphinic acid intermediates E. R. SQUIBB & SONS, INC. (US) 1986-07-22 US claimed
US-4497890-A APPLYING A LAYER OF CHELATING SILANE MOTOROLA, INC. (US) 1985-02-05 US claimed
EP-0113243-A2 Cephalosporin derivatives KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1984-07-11 EP claimed
US-4433142-A Process for the preparation of 7-(2-amino-2-phenylacetamido) cephem derivatives EISAI CO., LTD. (JP) 1984-02-21 US claimed
EP-0075928-A2 3-Carbamoyloxymethylcephem derivatives, processes for the preparation thereof, and antibacterial drugs containg same Eisai Co., Ltd. (JP) 1983-04-06 EP claimed
EP-0065270-A2 Process for the preparation of 7-(2-amino-2-phenylacetamido)cephem derivatives and their use for the preparation of antibacterial agents Eisai Co., Ltd. (JP) 1982-11-24 EP claimed
US-4355172-A Process for 4-(D-3-amino-3-carboxypropoxy)-phenylglyoxylic acid oxime derivatives ELI LILLY AND COMPANY (US) 1982-10-19 US claimed
US-4029883-A Dehydroxylation of aminosugars TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) 1977-06-14 US claimed
US-4020269-A Epiminodeaminodeoxyaminoglycoside antibiotics and intermediates TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) 1977-04-26 US claimed