SCHEMBL3258299

SCHEMBL3258299

C[Si](C)(C)CC(=O)NC(N)=O

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.42
TSHR P16473 2/20 0.30
NFKB1 P19838 2/20 0.30
CYP1A2 P05177 1/20 0.30
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30
THPO P40225 1/20 0.30
CA2 P00918 1/20 0.30
LMNA P02545 1/20 0.30
CYP3A4 P08684 1/20 0.30
CA5A P35218 1/20 0.30
BLM P54132 1/20 0.30
PMP22 Q01453 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL320488 0.75
SCHEMBL27934699 0.72 CRBN (0.56) CRBNTSHRNFKB1CYP1A2MAOA
SCHEMBL8503194 0.70
SCHEMBL3075326 0.70
SCHEMBL9428213 0.69 CRBN (0.52) CRBNTSHRNFKB1CYP1A2MAOA
Methyl Alcohol SCHEMBL27534230 0.69 CRBN (0.46) CRBNTSHRNFKB1CYP1A2MAOA
SCHEMBL3417873 0.69
Hydrochloric Acid SCHEMBL7131964 0.69
SCHEMBL3409286 0.69 CRBN (0.52) CRBNTSHRNFKB1CYP1A2MAOA
SCHEMBL1685402 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0564253-B1 Process for preparing alkoxy-terminated organosiloxane fluids using organo-lithium reagents LOCTITE CORP (US) 1998-12-09 EP claimed
WO-2010049451-A2 C-GLYCOSIDIC ANALOGUES OF ALPHA-GALACTOSYLCERAMIDS HAVING IMMUNOSTIMULATING AND IMMUNOREGULATING PROPERTIES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2010-05-06 WO disclosed
EP-0995743-B1 Derivatives of dihydro- and tetrahydrochinoline as a medicinal antioxydans SERVIER LAB (FR) 2003-04-02 EP disclosed
EP-0995743-A1 Derivatives of dihydro- and tetrahydrochinoline as a medicinal antioxydans ADIR ET COMPAGNIE (FR) 2000-04-26 EP disclosed