Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.48 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | PTAFR | P25105 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.40 |
| ▸ | PRKCG | P05129 | 1/20 | 0.40 |
| ▸ | PRKCB | P05771 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | PRKCH | P24723 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13491205 | 0.90 | FABP3 (0.48) | ALDH1A1SMN1; SMN2NR5A2NR5A1MAPT | |
| SCHEMBL29482557 | 0.82 | SMN1; SMN2 (0.67) | ALDH1A1SMN1; SMN2NR5A2NR5A1MAPT | |
| SCHEMBL2125477 | 0.82 | SMN1; SMN2 (0.67) | ALDH1A1SMN1; SMN2NR5A2NR5A1MAPT | |
| SCHEMBL3208533 | 0.81 | ADORA3 (0.40) | ALDH1A1MAPTRECQLMEN1LMNA | |
| SCHEMBL30884201 | 0.80 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2NR5A2NR5A1MAPT | |
| SCHEMBL29870836 | 0.80 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2NR5A2NR5A1MAPT | |
| SCHEMBL14780582 | 0.79 | SELP (0.43) | NR5A2NR5A1 | |
| SCHEMBL30536890 | 0.79 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2NR5A2NR5A1MAPT | |
| SCHEMBL235516 | 0.79 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2NR5A2NR5A1MAPT | |
| SCHEMBL29934680 | 0.79 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2NR5A2NR5A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399516-B2 | Alpha-substituted omega-3 lipids that are activators or modulators of the peroxisome proliferators-activated receptor (PPAR) | PRONOVA BIOPHARMA NORGE AS (NO) | 2013-03-19 | — | — | US | claimed |
| US-20100035990-A1 | ALPHA-SUBSTITUTED OMEGA-3 LIPIDS THAT ARE ACTIVATORS OR MODULATORS OF THE PEROXISOME PROLIFERATORS-ACTIVATED RECEPTOR (PPAR) | PRONOVA BIOPHARMA NORGE AS (NO) | 2010-02-11 | — | — | US | claimed |
| US-8399516-B2 | Alpha-substituted omega-3 lipids that are activators or modulators of the peroxisome proliferators-activated receptor (PPAR) | PRONOVA BIOPHARMA NORGE AS (NO) | 2013-03-19 | — | — | US | disclosed |
| US-20100035990-A1 | ALPHA-SUBSTITUTED OMEGA-3 LIPIDS THAT ARE ACTIVATORS OR MODULATORS OF THE PEROXISOME PROLIFERATORS-ACTIVATED RECEPTOR (PPAR) | PRONOVA BIOPHARMA NORGE AS (NO) | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035990-A1 | ALPHA-SUBSTITUTED OMEGA-3 LIPIDS THAT ARE ACTIVATORS OR MODULATORS OF THE PEROXISOME PROLIFERATORS-ACTIVATED RECEPTOR (PPAR) | PPARG, PPARA, FFAR3 | ALDH1A1 1088/4885SMN1; SMN2 3867/4885NR5A2 821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.