SCHEMBL3204958

SCHEMBL3204958

Cc1ccccc1NN=C(CC1C=Cc2ccccc21)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.35
MAPT P10636 5/20 0.35
TDP1 Q9NUW8 5/20 0.35
ALDH1A1 P00352 4/20 0.35
PKM P14618 1/20 0.35
SIGMAR1 Q99720 6/20 0.35
HPGD P15428 2/20 0.35
POLB P06746 1/20 0.35
HTR6 P50406 1/20 0.35
RAB9A P51151 1/20 0.35
HTT P42858 2/20 0.34
PTBP1 P26599 1/20 0.34
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CA4 P22748 1/20 0.32
CA9 Q16790 1/20 0.32
KMT2A Q03164 1/20 0.32
GAA P10253 3/20 0.31
LMNA P02545 2/20 0.31
KDM4E B2RXH2 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3192241 0.85 CYP3A4 (0.36) MAPTTDP1ALDH1A1SIGMAR1HPGD
SCHEMBL3207546 0.85 GAA (0.40) SMN1; SMN2MAPTTDP1ALDH1A1SIGMAR1
SCHEMBL3204439 0.84 MAPT (0.36) SMN1; SMN2MAPTTDP1ALDH1A1SIGMAR1
SCHEMBL3204928 0.80 KMT2A (0.39) SMN1; SMN2MAPTTDP1SIGMAR1HTR6
SCHEMBL3203313 0.80 SIGMAR1 (0.36) SIGMAR1HTR6
SCHEMBL3212484 0.78 MAPT (0.35) SMN1; SMN2MAPTTDP1ALDH1A1PKM
SCHEMBL3192235 0.78 CA1 (0.37) SMN1; SMN2MAPTTDP1ALDH1A1HPGD
SCHEMBL3214259 0.77 HPGD (0.41) SMN1; SMN2MAPTTDP1ALDH1A1PKM
SCHEMBL3199897 0.75 SMN1; SMN2 (0.34) SMN1; SMN2MAPTTDP1ALDH1A1PKM
SCHEMBL3215321 0.75 MEN1 (0.37) SMN1; SMN2ALDH1A1SIGMAR1HTR6RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7732643-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-08 US disclosed
US-7671226-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-02 US disclosed
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME HANAOKA HIDENORI 2010-02-25 US disclosed
EP-1426379-B1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME SUMITOMO CHEMICAL CO (JP) 2009-11-11 EP disclosed
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same HANAOKA HIDENORI 2009-02-26 US disclosed
US-7439379-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL CO., LTD. (JP) 2008-10-21 US disclosed
US-20040242410-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-02 US disclosed
EP-1426379-A1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME Sumitomo Chemical Company, Limited (JP) 2004-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same C1R, C1S, AP1M1 SMN1; SMN2 3599/4885MAPT 2641/4885TDP1 4304/4885
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME C1R, C1S, AP1M1 SMN1; SMN2 3599/4885MAPT 2641/4885TDP1 4304/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.