SCHEMBL3207546

SCHEMBL3207546

C1=CC(CC(=NNc2ccccc2)c2ccccc2)c2ccccc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 8/20 0.40
ALDH1A1 P00352 8/20 0.40
MAPT P10636 8/20 0.40
KMT2A Q03164 7/20 0.40
MEN1 O00255 6/20 0.40
KDM4E B2RXH2 4/20 0.40
TDP1 Q9NUW8 4/20 0.40
TAAR1 Q96RJ0 1/20 0.40
HPGD P15428 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
NPC1 O15118 2/20 0.39
HTT P42858 2/20 0.38
HTR6 P50406 1/20 0.38
CA2 P00918 5/20 0.37
CA1 P00915 4/20 0.37
CA4 P22748 4/20 0.36
CA9 Q16790 3/20 0.36
LMNA P02545 2/20 0.36
THRB P10828 1/20 0.36
SIGMAR1 Q99720 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3192235 0.87 CA1 (0.37) GAAALDH1A1MAPTKMT2AMEN1
SCHEMBL3204958 0.85 SMN1; SMN2 (0.35) GAAALDH1A1MAPTKMT2AKDM4E
SCHEMBL3203313 0.84 SIGMAR1 (0.36) HTR6SIGMAR1
SCHEMBL3204439 0.84 MAPT (0.36) GAAALDH1A1MAPTKMT2AMEN1
SCHEMBL3192241 0.82 CYP3A4 (0.36) GAAALDH1A1MAPTKMT2AMEN1
SCHEMBL3204928 0.82 KMT2A (0.39) MAPTKMT2AMEN1KDM4ETDP1
SCHEMBL3215321 0.79 MEN1 (0.37) ALDH1A1KMT2AMEN1SMN1; SMN2NPC1
SCHEMBL3202964 0.74 ALDH1A1 (0.47) GAAALDH1A1MAPTKMT2AMEN1
SCHEMBL3206071 0.74 CA1 (0.40) GAAALDH1A1MAPTKMT2AMEN1
SCHEMBL3202181 0.73 ALDH1A1 (0.38) GAAALDH1A1MAPTKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7732643-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-08 US disclosed
US-7671226-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-02 US disclosed
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME HANAOKA HIDENORI 2010-02-25 US disclosed
EP-1426379-B1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME SUMITOMO CHEMICAL CO (JP) 2009-11-11 EP disclosed
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same HANAOKA HIDENORI 2009-02-26 US disclosed
US-7439379-B2 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL CO., LTD. (JP) 2008-10-21 US disclosed
US-20040242410-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-02 US disclosed
EP-1426379-A1 TRANSITION METAL COMPLEX,CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME Sumitomo Chemical Company, Limited (JP) 2004-06-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054607-A1 Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same C1R, C1S, AP1M1 GAA 4642/4885ALDH1A1 1229/4885MAPT 2641/4885
US-20100048933-A1 TRANSITION METAL COMPLEX, CATALYST FOR OLEFIN POLYMERIZATION, AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME C1R, C1S, AP1M1 GAA 4642/4885ALDH1A1 1229/4885MAPT 2641/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.