Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.68 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.68 |
| ▸ | FAAH | O00519 | 4/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.62 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.59 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.58 |
| ▸ | TERT | O14746 | 3/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.58 |
| ▸ | PPARG | P37231 | 3/20 | 0.58 |
| ▸ | PPARD | Q03181 | 3/20 | 0.58 |
| ▸ | PPARA | Q07869 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | BLM | P54132 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3188942 | 0.93 | CNR2 (0.59) | CNR2TRPV1FAAHCYP1A2CYP2C19 | |
| SCHEMBL4016383 | 0.89 | HSP90AA1 (0.59) | CNR2TRPV1FAAHKMT2AMEN1 | |
| SCHEMBL6926300 | 0.89 | HSP90AA1 (0.59) | CNR2TRPV1FAAHKMT2AMEN1 | |
| SCHEMBL5792516 | 0.89 | HSP90AA1 (0.59) | CNR2TRPV1FAAHKMT2AMEN1 | |
| SCHEMBL6924837 | 0.89 | HSP90AA1 (0.59) | CNR2TRPV1FAAHKMT2AMEN1 | |
| SCHEMBL29539532 | 0.88 | CNR2 (0.69) | CNR2TRPV1FAAHCYP1A2CYP2C19 | |
| SCHEMBL19812439 | 0.88 | CNR2 (0.69) | CNR2TRPV1FAAHCYP1A2CYP2C19 | |
| SCHEMBL19812449 | 0.88 | CNR2 (0.69) | CNR2TRPV1FAAHCYP1A2CYP2C19 | |
| SCHEMBL13479772 | 0.87 | HSP90AA1 (0.56) | CNR2TRPV1FAAHKMT2AMEN1 | |
| SCHEMBL8496765 | 0.85 | CNR2 (0.75) | CNR2TRPV1FAAHCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662971-B2 | enzyme inhibitor for treating sleep disorders | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-02-16 | — | — | US | disclosed |
| EP-2093220-A2 | Inhibitors of fatty acid amide hydrolase | The Scripps Research Institute (US) | 2009-08-26 | — | — | EP | disclosed |
| EP-1549624-B1 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | SCRIPPS RESEARCH INST (US) | 2009-05-13 | — | — | EP | disclosed |
| US-20060111359-A1 | enzyme inhibitor for treating sleep disorders | THE SCRIPPS RESEARCH INSTITUTE (US) | 2006-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060111359-A1 | enzyme inhibitor for treating sleep disorders | FAAH, FAAH2, HCRTR2 | CNR2 4/4885TRPV1 664/4885FAAH 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.