Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5727096 | 0.84 | KDM4E (0.48) | ALDH1A1KDM4EHPGDHTTRECQL | |
| SCHEMBL3373723 | 0.84 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDHTTRECQL | |
| SCHEMBL22263358 | 0.84 | KDM4E (0.42) | ALDH1A1KDM4EHPGDHTTRECQL | |
| SCHEMBL16101517 | 0.84 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDHTTRECQL | |
| SCHEMBL16268429 | 0.84 | LMNA (0.55) | ALDH1A1CYP1A2CYP2C9CYP2C19MAPT | |
| SCHEMBL7885220 | 0.82 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDHTTRECQL | |
| SCHEMBL27094259 | 0.81 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDHTTRECQL | |
| SCHEMBL7885491 | 0.79 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDHTTRECQL | |
| SCHEMBL7309272 | 0.79 | ALDH1A1 (0.49) | ALDH1A1KDM4EHPGDHTTRECQL | |
| SCHEMBL21880014 | 0.79 | KDM4E (0.40) | ALDH1A1KDM4EHPGDHTTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7667035-B2 | Imidazole derivatives, their preparation and their use as intermediates for the preparation of pharmaceutical compositions and pesticides | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-02-23 | — | — | US | disclosed |
| US-7667035-B2 | Imidazole derivatives, their preparation and their use as intermediates for the preparation of pharmaceutical compositions and pesticides | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-02-23 | — | — | US | disclosed |
| US-7667035-B2 | Imidazole derivatives, their preparation and their use as intermediates for the preparation of pharmaceutical compositions and pesticides | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-02-23 | — | — | US | disclosed |
| US-20090023920-A1 | IMIDAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INTERMEDIATES FOR THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS AND PESTICIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-01-22 | — | — | US | disclosed |
| US-20090023920-A1 | IMIDAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INTERMEDIATES FOR THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS AND PESTICIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-01-22 | — | — | US | disclosed |
| US-20090023920-A1 | IMIDAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INTERMEDIATES FOR THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS AND PESTICIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-01-22 | — | — | US | disclosed |
| US-7439370-B2 | Imidazole derivatives, their preparation and their use as intermediates for the preparation of pharmaceutical compositions and pesticides | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-10-21 | — | — | US | disclosed |
| US-7439370-B2 | Imidazole derivatives, their preparation and their use as intermediates for the preparation of pharmaceutical compositions and pesticides | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-10-21 | — | — | US | disclosed |
| US-7439370-B2 | Imidazole derivatives, their preparation and their use as intermediates for the preparation of pharmaceutical compositions and pesticides | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-10-21 | — | — | US | disclosed |
| US-20050261352-A1 | Imidazole derivatives, their preparation and their use as intermediates for the preparation of pharmaceutical compositions and pesticides | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-11-24 | — | — | US | disclosed |
| WO-2005110999-A1 | NOVEL IMIDAZOLE DERIVATIVES, THE PRODUCTION THEREOF, AND THE USE OF THE SAME AS INTERMEDIATE PRODUCTS FOR PRODUCING MEDICAMENTS AND PESTICIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2005-11-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261352-A1 | Imidazole derivatives, their preparation and their use as intermediates for the preparation of pharmaceutical compositions and pesticides | CHRM1, CHRM2, CYP3A43 | ALDH1A1 1775/4885KDM4E 2469/4885HPGD 1542/4885 |
| US-20090023920-A1 | IMIDAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INTERMEDIATES FOR THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS AND PESTICIDES | CHRM1, CHRM2, CYP3A43 | ALDH1A1 1775/4885KDM4E 2469/4885HPGD 1542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.