Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3687592 | 0.89 | ALDH1A1 (0.32) | ALDH1A1TSHRHTR7 | |
| Hydrochloric Acid SCHEMBL3207930 | 0.82 | TSHR (0.33) | ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL3194019 | 0.81 | KDM4E (0.31) | — | |
| Hydrochloric Acid SCHEMBL3214579 | 0.79 | CYP2D6 (0.32) | TSHR | |
| Hydrochloric Acid SCHEMBL3192699 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL3210117 | 0.73 | CYP1A2 (0.32) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3205221 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL3200218 | 0.71 | TSHR (0.31) | TSHR | |
| Hydrochloric Acid SCHEMBL3210126 | 0.69 | SLC6A2 (0.31) | — | |
| Hydrochloric Acid SCHEMBL3209790 | 0.69 | HTT (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7671226-B2 | Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-03-02 | — | — | US | disclosed |
| US-7439379-B2 | Transition metal complex, catalyst for olefin polymerization, and process for producing olefin polymer with the same | SUMITOMO CHEMICAL CO., LTD. (JP) | 2008-10-21 | — | — | US | disclosed |