SCHEMBL3205171

SCHEMBL3205171

O=C(CCC1C2CCC1CN(Cc1ccccc1)C2)Oc1cccc(C2CCCCCC2)c1O

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 1/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
GRIN2B Q13224 4/20 0.37
CHRM4 P08173 1/20 0.36
TBXA2R P21731 1/20 0.36
PRMT5 O14744 1/20 0.36
WDR77 Q9BQA1 1/20 0.36
BCHE P06276 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5116052 0.78 DRD2 (0.51) MEN1KMT2ACHRM4BCHE
SCHEMBL3217075 0.77 BCHE (0.37) PTGDR2GRIN2BTBXA2RBCHE
SCHEMBL3205175 0.77 BCHE (0.37) PTGDR2GRIN2BTBXA2RBCHE
SCHEMBL4179654 0.76 BCHE (0.38) MEN1KMT2AGRIN2BTBXA2RBCHE
SCHEMBL4193805 0.75 GRIN2B (0.38) PTGDR2MEN1KMT2AGRIN2BTBXA2R
SCHEMBL4190993 0.74 GRIN2B (0.39) MEN1KMT2AGRIN2BTBXA2RBCHE
SCHEMBL5115681 0.69 TACR3 (0.52)
SCHEMBL5116054 0.66 BCHE (0.47) MEN1KMT2ABCHE
SCHEMBL3681668 0.66 PTGDR2 (0.46) PTGDR2MEN1KMT2ATBXA2R
SCHEMBL20399604 0.66 GRIN2B (0.46) GRIN2BBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100056496-A1 MUSCARINIC RECEPTOR ANTAGONISTS RANBAXY LABORATORIES LIMITED (IN) 2010-03-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100056496-A1 MUSCARINIC RECEPTOR ANTAGONISTS CHRM3, CHRM5, CHRM2 PTGDR2 297/4885MEN1 1810/4885KMT2A 3389/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.