Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29030940 | 0.86 | S1PR1 (0.48) | S1PR1S1PR5 | |
| SCHEMBL29030939 | 0.86 | S1PR1 (0.48) | S1PR1S1PR5 | |
| SCHEMBL20399839 | 0.82 | GRIN2B (0.49) | GRIN2BS1PR1S1PR5 | |
| SCHEMBL6726017 | 0.80 | NR1H2 (0.51) | S1PR1S1PR5BCHEACHEMAOB | |
| SCHEMBL26109889 | 0.79 | BCHE (0.52) | GRIN2BBCHEACHEMAOB | |
| SCHEMBL8446486 | 0.78 | LTA4H (0.65) | BCHEACHEMAOB | |
| SCHEMBL4189224 | 0.78 | GRIN2B (0.48) | GRIN2BS1PR1S1PR5 | |
| SCHEMBL2980930 | 0.78 | DRD2 (0.67) | BCHEACHEMAOB | |
| SCHEMBL4198217 | 0.76 | FUCA1 (0.54) | GRIN2BS1PR1S1PR5BCHEACHE | |
| SCHEMBL19971633 | 0.76 | ALDH1A1 (0.53) | GRIN2BS1PR1S1PR5BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018136887-A1 | COMPOUNDS | TESARO, INC. (US) | 2018-07-26 | — | — | WO | disclosed |