Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AQP1 | P29972 | 2/20 | 0.50 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3205155 | 1.00 | AQP1 (0.50) | AQP1PDE3BPDE3AHTR2AHTR2C | |
| SCHEMBL3216276 | 1.00 | AQP1 (0.50) | AQP1PDE3BPDE3AHTR2AHTR2C | |
| SCHEMBL3208760 | 0.90 | AQP1 (0.40) | AQP1PDE3BPDE3A | |
| SCHEMBL3207403 | 0.90 | AQP1 (0.40) | AQP1PDE3BPDE3A | |
| SCHEMBL3195090 | 0.90 | AQP1 (0.40) | AQP1PDE3BPDE3A | |
| SCHEMBL3209871 | 0.88 | AQP1 (0.39) | AQP1 | |
| SCHEMBL3199609 | 0.88 | AQP1 (0.39) | AQP1 | |
| SCHEMBL3209724 | 0.88 | AQP1 (0.39) | AQP1 | |
| SCHEMBL3222278 | 0.87 | AQP1 (0.38) | AQP1PDE3BPDE3A | |
| SCHEMBL3207825 | 0.87 | AQP1 (0.38) | AQP1PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100035871-A1 | BENZOXAZINE DERIVATIVES AND USES THEREOF | WYETH | 2010-02-11 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035871-A1 | BENZOXAZINE DERIVATIVES AND USES THEREOF | HTR2C, HTR5A, NPY1R | AQP1 2125/4885PDE3B 718/4885PDE3A 717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.