SCHEMBL3205447

SCHEMBL3205447

Cc1c(Cl)cc(Cl)c2sc3ccccc3c(=O)c12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.50
ALDH1A1 P00352 6/20 0.50
POLB P06746 3/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
GAA P10253 1/20 0.50
HCRTR1 O43613 2/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
LMNA P02545 1/20 0.48
KDM4E B2RXH2 4/20 0.46
MAOA P21397 2/20 0.43
MAOB P27338 1/20 0.43
NPC1 O15118 3/20 0.40
RAB9A P51151 3/20 0.40
HPGD P15428 3/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
NFKB1 P19838 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8086616 0.90 MAPT (0.52) MAPTALDH1A1POLBMEN1KMT2A
SCHEMBL8091812 0.81 MAPT (0.50) MAPTALDH1A1POLBMEN1KMT2A
SCHEMBL26194151 0.79 MAPT (0.53) MAPTALDH1A1POLBMEN1KMT2A
SCHEMBL28800533 0.78 MAPT (0.57) MAPTALDH1A1POLBMEN1KMT2A
SCHEMBL30913888 0.78 MAPT (0.57) MAPTALDH1A1POLBMEN1KMT2A
SCHEMBL8096726 0.77 MAPT (0.51) MAPTALDH1A1POLBMEN1KMT2A
SCHEMBL16383368 0.77 MAPT (0.52) MAPTALDH1A1POLBMEN1KMT2A
SCHEMBL3160057 0.77 ALDH1A1 (0.62) MAPTALDH1A1POLBMEN1KMT2A
SCHEMBL9127550 0.76 KDM4E (0.41) MAPTALDH1A1POLBMEN1KMT2A
SCHEMBL8089980 0.76 MAPT (0.51) MAPTALDH1A1POLBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100047451-A1 ACTINIC-RADIATION CURABLE INK COMPOSITION, INK SET, INK JET PRINTING APPARATUS, AND INK JET RECORDING METHOD USING ACTINIC-RADIATION CURABLE INK COMPOSITION SEIKO EPSON CORPORATION 2010-02-25 US disclosed